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Ocular Hypertension clinical trials

View clinical trials related to Ocular Hypertension.

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NCT ID: NCT01291108 Completed - Ocular Hypertension Clinical Trials

Safety and Efficacy of AGN-210669 Ophthalmic Solution Compared With Bimatoprost Ophthalmic Solution in Patients With Open-Angle Glaucoma or Ocular Hypertension

Start date: April 2011
Phase: Phase 2
Study type: Interventional

This study will evaluate the safety and efficacy of AGN-210669 ophthalmic solution compared with bimatoprost ophthalmic solution (Lumigan®) as monotherapy and adjunctive therapy in patients with primary open-angle glaucoma or ocular hypertension.

NCT ID: NCT01281020 Completed - Ocular Hypertension Clinical Trials

Adherence With Fixed Versus Unfixed Glaucoma Therapy

Start date: May 2009
Phase:
Study type: Observational

A 6-month, parallel, non-interventional trial investigating the level of adherence and the impact of dosing in open-angle glaucoma patients who receive either unfixed therapy with latanoprost once in the evening and timolol twice daily, or latanoprost/timolol fixed combination therapy once in the evening. All patients participating in this observational study will be monitored for their adherence with the use of Medication Event Monitoring System (MEMS). At the end of treatment periods treatment satisfaction will be assessed with selected questions from the Treatment Satisfaction Survey-Intraocular Pressure survey. This study will monitor objectively, for the first time, adherence and intraocular pressure control with fixed versus unfixed therapy. Finally it will help us to elucidate the impact of dosing (once-a-day versus three-times-daily) on the level of adherence in glaucoma.

NCT ID: NCT01279083 Completed - Ocular Hypertension Clinical Trials

Safety and Efficacy Trial to Treat Open-Angle Glaucoma or Ocular Hypertension

Start date: January 2011
Phase: Phase 1/Phase 2
Study type: Interventional

To investigate the safety and efficacy of DE-112 in lowering intraocular pressure in subjects with primary open-angle glaucoma or ocular hypertension.

NCT ID: NCT01271686 Completed - Glaucoma Clinical Trials

24-hour IOP-lowering Effect of 0.01% Bimatoprost

Start date: January 2011
Phase: Phase 4
Study type: Interventional

This study will evaluate the 24-hour IOP-lowering efficacy of 0.01% bimatoprost once daily in patients with glaucoma or ocular hypertension

NCT ID: NCT01265719 Completed - Glaucoma Clinical Trials

Long-Term Non-Interventional Latanoprost Study

LYNX
Start date: December 2010
Phase:
Study type: Observational

This is a non-interventional, prospective, longitudinal cohort study. A total of 150 pediatric subjects with glaucoma or elevated intraocular pressure, including 75 latanoprost-treated subjects and 75 non-topical prostaglandin analogue treated subjects, will be enrolled from ophthalmic hospital clinics and academic ophthalmic centers. As a non-interventional study, the study subjects' continued use of latanoprost and assessments of ocular events will be obtained through the routine medical follow-up with treating ophthalmologists or other designated members of the medical care team.

NCT ID: NCT01263444 Completed - Glaucoma Clinical Trials

Safety and Efficacy of Adding AZARGA® Adjunctive to Prostaglandin Therapy

Start date: March 2011
Phase: Phase 4
Study type: Interventional

The purpose of this study was to evaluate the safety and efficacy of adding AZARGA® as a single agent to prostaglandin monotherapy in patients with either ocular hypertension or primary open-angle glaucoma.

NCT ID: NCT01261871 Completed - Ocular Hypertension Clinical Trials

Intraocular Pressure During Robotic Assisted Laparoscopic Procedures Utilizing Steep Trendelenburg Positioning

Start date: December 2008
Phase: N/A
Study type: Observational

The purpose of this study is to measure pressures within the eye (during surgery to remove the prostate or abdominopelvic masses) as the body position required for these laparoscopic procedures has been associated with increases in pressure within the eye.

NCT ID: NCT01254604 Completed - Glaucoma Clinical Trials

Preservative-Free Tafluprost (MK-2452) for the Treatment of Open-Angle Glaucoma or Ocular Hypertension (MK-2452-002)

Start date: December 1, 2011
Phase: Phase 3
Study type: Interventional

This study will test the hypothesis that preservative-free tafluprost (MK-2452) is non-inferior to preservative-free timolol maleate with respect to the diurnal intraocular pressure (IOP) change from baseline after 4 weeks of therapy in participants with open-angle glaucoma or ocular hypertension.

NCT ID: NCT01254370 Completed - Clinical trials for Ocular Surface Disease

Safety and Efficacy Study of Catioprost® (Unpreserved Latanoprost 0.005% Emulsion) Compared to Travatan Z® to Treat Glaucoma and Ocular Surface Disease

Start date: November 2010
Phase: Phase 2
Study type: Interventional

The purpose of this study is to compare: - the effect of Catioprost® and Travatan Z® on the ocular surface disease (OSD) in subjects with glaucoma or ocular hypertension and ocular surface disease. - the intraocular pressure (IOP) lowering effect and safety of Catioprost® and Travatan Z® in subjects with glaucoma or ocular hypertension and ocular surface disease.

NCT ID: NCT01253902 Completed - Ocular Hypertension Clinical Trials

Ocular Surface Tolerability Study of Prostaglandin Analogues in Patients With Open-Angle Glaucoma or Ocular Hypertension

Start date: December 2010
Phase: Phase 4
Study type: Interventional

This study evaluated the ocular surface tolerability of the prostaglandin analogues bimatoprost ophthalmic solution 0.01% (Lumigan® 0.01%), travoprost ophthalmic solution 0.004% (Travatan Z®) and latanoprost ophthalmic solution 0.005% (Xalatan®) in patients previously treated with Xalatan® who have open-angle glaucoma or ocular hypertension.