Occupational Asthma Clinical Trial
Official title:
Evolution of the Incidence of Occupational Asthma at the Beginning of the Activity of Young Bakers, Pastry-makers and Hairdressers, and Exploration of Its Risk Factors
Background: Occupational exposures are thought to be responsible for 10-15% of new-onset
asthma cases in adults, with disparities across sectors. Because most of the data are
derived from registries and cross-sectional studies, little is known about incidence of
occupational asthma (OA) during the first years after inception of exposure. This study
focuses on this early asthma onset period among young workers in the bakery, pastry making
and hairdressing sectors in order to assess early incidence of OA in these "at risk"
occupations according to exposure duration, and to identify risk factors of OA.
Methods: This study is a longitudinal retrospective study with a nested case-control to
identify risk factors of OA. The assessment of incidence evolution is made by exploring a
series of promotions (or retrospective cohorts) with increasing duration since at work. The
study population is composed of subjects who graduated between 2001 and 2006 in sectors
where they experience exposure to organic or inorganic allergenic or irritant compounds
(with an objective of 150 subjects by year) and 250 young workers with no specific
occupational exposure.
This study is a descriptive, monocentric, longitudinal and retrospective study with
cross-sectional measurements.
n/a
Observational Model: Cohort, Time Perspective: Retrospective
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| Terminated |
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N/A | |
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