Clinical Trials Logo
  1. Home
  2. Obstructive Sleep Apnea (OSA)
  3. NCT01249924

The Effectiveness of Perioperative CPAP to Reduce Obstructive Sleep Apnea Related Adverse Events

Obstructive Sleep Apnea (OSA) Clinical Trial

Official title:
The Effectiveness of Perioperative CPAP to Reduce the Occurrence of Sleep Apnea Related Adverse Events in Surgical Patients With Obstructive Sleep Apnea

Clinical Trial Summary

Objective of the study: To determine whether Perioperative Auto-CPAP treatment prevent postoperative worsening of OSA and improve nocturnal oxygen saturation in surgical patients with moderate and severe OSA.

Clinical Trial Description

The patients will be approached by the study coordinators at the preoperative clinic. If the patient is interested in participating the study, STOP-Bang and Epworth questionnaires will be implemented to determine the risk for OSA.If the patients are classified as high risk of having OSA, they are scheduled for an overnight sleep study at home. The patients with Apnea-Hypopnea Index (AHI)>15 from the sleep study will be randomized into two study groups: Perioperative CPAP group or control group (routine care). In the perioperative CPAP group, patients will be treated with auto-CPAP for 2-3 nights preoperatively and 5 nights postoperatively. All patients will undergo sleep study on the third postoperative night and be monitored by a pulse oximeter for 2-3 nights preoperatively and 5 nights postoperatively. ;

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01249924
Study type Interventional
Source University Health Network, Toronto
Contact
Status Completed
Phase N/A
Start date October 2009
Completion date October 2011
View Details
See also
  Status Clinical Trial Phase
Not yet recruiting NCT04939168 - Measuring Atomoxetine and Aroxybutynin In Patients With OSA Phase 2
Completed NCT02908529 - Atomoxetine and Oxybutynin in Obstructive Sleep Apnea Phase 1/Phase 2
Completed NCT03415633 - Validity of a Home Respiratory Polygraphy for the Diagnosis of Obstructive Sleep Apnea N/A
Completed NCT03426631 - DAW1033B2 in Obstructive Sleep Apnea Phase 1/Phase 2
Completed NCT04206449 - Sleep Thermography for Diagnosis of Obstructive Sleep Apnea (TERMOAPNEA) N/A
Active, not recruiting NCT03018912 - Validating the Use of a Subjectively Reported Sleep Vital Sign N/A
Completed NCT02549508 - Comparison Study Using APAP With and Without SensAwake in Patients With OSA and PTSD N/A
Completed NCT00773721 - Foam Mask - Assessment of Bioburden in a New Mask Seal Material N/A
Completed NCT02314858 - Tailored Treatment to Enhance Risk Perception in Sleep Apnea N/A
Completed NCT01476917 - The ATLAST Long-Term Study Phase 2/Phase 3
Terminated NCT00730041 - Palatal Implants in Combination With Continuous Positive Airway Pressure to Treat Obstructive Sleep Apnea Phase 4
Completed NCT00850434 - Improved Automatic CPAP Algorithm to Treat Obstructive Sleep Apnea (OSA) N/A
Enrolling by invitation NCT04538755 - DAW2020 on OSA Endotypic Traits Phase 1/Phase 2
Completed NCT02501304 - Feasibility Study of the ReVENT Sleep Apnea System N/A
Withdrawn NCT02805777 - Vent Flow Study of Prototype Nasal CPAP Mask N/A
Completed NCT02097212 - Correlation Between Trachebroncho Malacia/Hyperdynamic Airway Collapse And Obstructive Sleep Apnea N/A
Active, not recruiting NCT02295306 - Overnight Polysomnography and Respiratory Volume Monitor
Terminated NCT01877928 - Post-extubation Boussignac CPAP System in Adults With Moderate to Severe Obstructive Sleep Apnea N/A
Completed NCT01939938 - Pilot Study of the Comparison of the Upper Airway Dynamics of Oronasal vs Nasal Masks With PAP Treatment N/A
Completed NCT00965783 - Predictors of the Metabolic Effect of Sleep Loss N/A