Improved Automatic CPAP Algorithm to Treat Obstructive Sleep Apnea (OSA)

Status Completed

Clinical Trial Summary

The purpose of this study is to compare a modified AutoSet algorithm running on research hardware versus the traditional AutoSet algorithm running on an S7 AutoSet Spirit. The study will determine if the modified AutoSet algorithm reacts appropriately to obstructive apnoeas and hypopnoeas and provides suitable levels of positive airway pressure compared to the S7 AutoSet Spirit. The hypothesis is that the modified AutoSet algorithm will be more efficacious than the traditional AutoSet algorithm

Clinical Trial Description

Subjects in the trial will spend 2 nights in a sleep laboratory being monitored with a full montage polysomnograph (PSG) with each of the algorithms providing positive airway pressure therapy. The PSG records EEG, EMG, EOG, patient airflow, respiratory effort, blood oxygen saturation, and body position. In a randomised order each subject will spend one night being treated by the modified AutoSet algorithm and a second night being treated by the traditional AutoSet algorithm. The subjects will be blinded to which therapy they are receiving and the scorer of the PSG will also be blinded to which therapy is being used. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00850434
Study type	Interventional
Source	ResMed
Contact
Status	Completed
Phase	N/A
Start date	November 2005
Completion date	November 2008

View Details

See also
Status	Clinical Trial	Phase
Not yet recruiting	`NCT04939168` - Measuring Atomoxetine and Aroxybutynin In Patients With OSA	Phase 2
Completed	`NCT02908529` - Atomoxetine and Oxybutynin in Obstructive Sleep Apnea	Phase 1/Phase 2
Completed	`NCT03415633` - Validity of a Home Respiratory Polygraphy for the Diagnosis of Obstructive Sleep Apnea	N/A
Completed	`NCT03426631` - DAW1033B2 in Obstructive Sleep Apnea	Phase 1/Phase 2
Completed	`NCT04206449` - Sleep Thermography for Diagnosis of Obstructive Sleep Apnea (TERMOAPNEA)	N/A
Active, not recruiting	`NCT03018912` - Validating the Use of a Subjectively Reported Sleep Vital Sign	N/A
Completed	`NCT02549508` - Comparison Study Using APAP With and Without SensAwake in Patients With OSA and PTSD	N/A
Completed	`NCT01249924` - The Effectiveness of Perioperative CPAP to Reduce Obstructive Sleep Apnea Related Adverse Events	N/A
Completed	`NCT00773721` - Foam Mask - Assessment of Bioburden in a New Mask Seal Material	N/A
Completed	`NCT02314858` - Tailored Treatment to Enhance Risk Perception in Sleep Apnea	N/A
Completed	`NCT01476917` - The ATLAST Long-Term Study	Phase 2/Phase 3
Terminated	`NCT00730041` - Palatal Implants in Combination With Continuous Positive Airway Pressure to Treat Obstructive Sleep Apnea	Phase 4
Enrolling by invitation	`NCT04538755` - DAW2020 on OSA Endotypic Traits	Phase 1/Phase 2
Completed	`NCT02501304` - Feasibility Study of the ReVENT Sleep Apnea System	N/A
Withdrawn	`NCT02805777` - Vent Flow Study of Prototype Nasal CPAP Mask	N/A
Completed	`NCT02097212` - Correlation Between Trachebroncho Malacia/Hyperdynamic Airway Collapse And Obstructive Sleep Apnea	N/A
Active, not recruiting	`NCT02295306` - Overnight Polysomnography and Respiratory Volume Monitor
Terminated	`NCT01877928` - Post-extubation Boussignac CPAP System in Adults With Moderate to Severe Obstructive Sleep Apnea	N/A
Completed	`NCT01939938` - Pilot Study of the Comparison of the Upper Airway Dynamics of Oronasal vs Nasal Masks With PAP Treatment	N/A
Completed	`NCT00965783` - Predictors of the Metabolic Effect of Sleep Loss	N/A