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Obstructive Sleep Apnea (OSA) clinical trials

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NCT ID: NCT04538755 Enrolling by invitation - Clinical trials for Obstructive Sleep Apnea (OSA)

DAW2020 on OSA Endotypic Traits

SedOSA
Start date: November 15, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

Obstructive sleep apnea (OSA) is common and has major health implications but treatment options are limited. Some OSA patients with low arousal threshold wake up prematurely during an obstructive event and do not have time for spontaneous upper airway (UA) dilator muscle recruitment. As a consequence they are exposed to apnea and hypopnea cycling. In this protocol the investigators will test the effect of DAW2020 administered before sleep on OSA phenotype traits and OSA severity during sleep.