Isovolumetric and Isocaloric Preloads of Various Types of Milk on Food Intake, Subjective Appetite and Glycemic Response

Obesity Prevention Clinical Trial

Official title:

The Effects of Isovolumetric and Isocaloric Preloads of Various Types of Milk on Food Intake, Subjective Appetite and Glycemic Response in Healthy Young Men and Women

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01025557
• Other study ID #: Milk Study - Experiment 1
• Secondary ID: DFO_24235
• Status: Completed
• Phase: Phase 1/Phase 2
• First received: December 2, 2009
• Last updated: June 13, 2012
• Start date: September 2009
• Est. completion date: May 2012

Study information

• Verified date: June 2012
• Source: University of Toronto
• Contact: n/a
• Is FDA regulated: No
• Health authority: Canada: Health Canada
• Study type: Interventional

Clinical Trial Summary

The purpose of this protocol is to study the effects of fluid milk products on satiety, food intake, and glucose metabolism in healthy young men and women. Experiment 1: The specific objective is to investigate isovolumetric amounts of milk (2% M.F.), chocolate milk (1% M.F.), a soy beverage, cow's milk-based infant formula, and water (control) on satiety and food intake and on blood glucose before and after a meal. A fixed volume approach is based on the commercially available serving size. Experiment 2 will examine equicaloric amounts of milk (2% M.F.), chocolate milk (1% M.F.), a soy beverage, cow's milk-based infant formula, a glucose drink and water (control) the treatments in order to investigate macronutrient composition on satiety and food intake and on blood glucose before and after the meal.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 52
• Est. completion date: May 2012
• Est. primary completion date: June 2011
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 20 Years to 30 Years

Eligibility

Inclusion Criteria:

• Healthy

• Non-smoking

• Aged 20-30 years

• Body mass index between 20 and 24.9 kg/m2

Exclusion Criteria:

• Diabetes

• Medication

• Lactose-intolerance or allergies to milk

• Breakfast skippers and those on an energy restricted diet

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Single Blind (Investigator), Primary Purpose: Basic Science

Related Conditions & MeSH terms

• Diabetes Prevention
• Obesity Prevention

Intervention

Other:
• Dietary intervention
Dietary treatments with beverages

Locations

Country	Name	City	State
Canada	University of Toronto	Toronto	Ontario

Sponsors (4)

Lead Sponsor	Collaborator
University of Toronto	Dairy Farmers of Ontario, Mondelez International, Inc., Natural Sciences and Engineering Research Council, Canada

Country where clinical trial is conducted

Canada, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Food intake		30 minute	No
Secondary	Blood glucose		0, 10, 20, 30, 50, 80, 110, 140 and 170 minutes	No