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Outcomes of RV Dysfunction in Acute Exacerbation of Chronic Respiratory Diseases — DVD  

Interstitial Lung Disease Clinical Trial

Official title:
Prevalence of Right Ventricular Dysfunction in Acute Exacerbation of Chronic Respiratory Diseases and Its Impact on Outcomes

Clinical Trial Summary

Observational study in patients with chronic respiratory diseases (chronic obstructive pulmonary diseases, bronchiectasis, interstitial lung diseases, neuromuscular diseases, obesity-hypoventilation syndrome...) admitted in intensive care unit for acute respiratory failure. The main objective is to determine the prevalence of right ventricular (RV) dysfunction in this population and to analyze the impact of such a complication on outcomes (survival at day-28, duration of non-invasive or mechanical ventilation, duration of hospital stay). RV function will be assessed by echocardiography at admission, after 3 days and at discharge. Plasma NT-proBNP and troponin levels will be collected.

Clinical Trial Description

Observational study in patients with chronic respiratory diseases (chronic obstructive pulmonary diseases, bronchiectasis, interstitial lung diseases, neuromuscular diseases, obesity-hypoventilation syndrome...) admitted in intensive care unit for acute respiratory failure. Inclusion Criteria: - Chronic respiratory disease (COPD, ILD, OHS...) - Admission in ICU for acute respiratory failure - Patient's non-opposition Exclusion Criteria: - Patients < 18 year-old - Protected patients - Pregnant women The main objective is to determine the prevalence of right ventricular (RV) dysfunction in this population and to analyze the impact of such a complication on outcomes (survival at day-28, duration of non-invasive or mechanical ventilation, duration of hospital stay). RV function will be assessed by echocardiography at admission, after 3 days and at discharge. Plasma NT-proBNP and troponin levels will be collected. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04098094
Study type Observational
Source Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil
Contact Athénaïs Boucly, MD
Phone +33669286528
Email athenais.boucly@gmail.com
Status Recruiting
Phase
Start date September 19, 2019
Completion date October 30, 2022
View Details
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