Obese Subjects Who Will Undergo Gastric By-pass Surgery Clinical Trial
Official title:
Effect of Bariatric Surgery on Kidney Function
Primary hypothesis:
A large reduction in weight is not associated with a change in accurately measured glomerular
filtration rate (GFR) (51Chromium ethylenediaminetetraacetic acid plasma clearance
(51Cr-EDTA)).
Secondary hypothesis:
A large reduction in weight is associated with a greater change in estimated GFR (The
Modification of Diet in Renal Disease (MDRD-formula)) than in accurately measured GFR.
Other formulas for estimated GFR (Cockcroft Gault, Chronic Kidney Disease Epidemiology
Collaboration (CKD-EPI), CKD-EPI with cystatin C) are better correlated with accurately
measured GFR.
n/a