Clinical Trials Logo

Nosocomial Infection clinical trials

View clinical trials related to Nosocomial Infection.

Filter by:

NCT ID: NCT01110421 Terminated - Clinical trials for Pneumonia, Bacterial

A Safety and Tolerability Study of Doripenem Compared With Cefepime in Hospitalized Children With Bacterial Pneumonia

Start date: December 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and tolerability of doripenem compared to cefepime in children hospitalized with pneumonia.

NCT ID: NCT01050608 Completed - Clinical trials for Nosocomial Infection

Evaluation of Body-worn Multimodal Hand Hygiene System. Impact on Health-Care Associated Infections

Sprixx-ICU
Start date: December 2007
Phase: N/A
Study type: Observational

Evaluate the efficacy of a multimodal hand hygiene system in the intensive care unit environment and evaluate any impact on health care associated infections.

NCT ID: NCT01046656 Completed - Diarrhea Clinical Trials

L Reuteri for the Prevention of Nosocomial Diarrhea

PND
Start date: December 2009
Phase: Phase 3
Study type: Interventional

Nosocomial diarrhea is any diarrhea that a patient contracts in a health-care institution. In children, it is commonly caused by enteric pathogens, especially rotavirus. The reported incidence ranges from 4.5 to 22.6 episodes per 100 admissions. Nosocomial diarrhea may prolong the hospital stay and increase medical costs. One of the potential strategies for the prevention of nosocomial infections is the use of probiotics. The number of studies have shown the efficacy of Lactobacillus reuteri (DSM 17938) in the treatment of acute diarrhea. However, there are no data on the efficacy of L. reuteri in the prevention of nosocomial diarrhea. The investigators, therefore, plan to perform the study with the aim of evaluating the role of Lactobacillus reuteri DSM 17938 administration in the prevention of nosocomial gastroenteritis in a pediatric hospital setting.

NCT ID: NCT00917319 Active, not recruiting - Clinical trials for Nosocomial Infection

Prevention and Control of Healthcare-Associated Infections

Start date: January 2009
Phase: N/A
Study type: Interventional

Bundling infection control interventions should decrease incidence of Healthcare-Associated Infections in General Medical Wards at Siriraj Hospital, Bangkok, Thailand

NCT ID: NCT00864929 Completed - Clinical trials for Nosocomial Infection

An Epidemiological Study on Antimicrobial Treatment of Nosocomial Infections in Clinical Practice

Start date: November 2009
Phase: N/A
Study type: Observational

The present study is a retrospective cohort study on patients who suffered a nosocomial infection in major hospitals in Vietnam. Data relating to patient demography include age, gender; medical history; APACHE II score; background conditions, infection details and antimicrobial therapy; and all-caused mortality, time of hospitalization and intensive care. The investigators hypothesis is that antimicrobial treatment inappropriate is highly dependent on incidence of antibiotic resistant pathogens, nonfermentative Gram-negative bacilli and ESBL-producing enterobacteriaceae spp. Variables are demographic characteristics, background conditions, immunosuppressive therapy, antimicrobial susceptibility and inappropriate treatment is explored as possible predictors of mortality.

NCT ID: NCT00727363 Terminated - Death Clinical Trials

Prophylactic Probiotics in Premature Infants

C3P
Start date: August 2008
Phase: Phase 3
Study type: Interventional

This study tries to determine whether the oral administration of a specific probiotic (good bacteria) in premature infants hospitalized in a neonatal intensive care unit may prevent infections and the development of a severe inflammatory disease of the bowel called necrotizing enterocolitis. The investigators propose that premature infants not given probiotics will colonize their gut with bad bacterias and develop infection.

NCT ID: NCT00701948 Completed - Clinical trials for Nosocomial Infection

New Dosages of Inflammatory Markers for the Early Diagnosis of Nosocomial Bacterial Infections of the Newborn

NOSODIAG
Start date: July 2008
Phase:
Study type: Observational

This study aims to evaluate new dosage of inflammatory markers or new inflammatory markers for the diagnosis of nosocomial bacterial infection. We made the hypothesis that these new dosages or new inflammatory markers could be more useful than dosage of inflammatory markers already used in clinical practice (especially the use of a combination of interleukins (6 or 8) and C-reactive protein for the management of newborns with a clinical suspicion of nosocomial bacterial infection and especially could allow to avoid excessive treatment with antibiotics

NCT ID: NCT00563186 Completed - Clinical trials for Clostridium Difficile Infection

Hospital Design and Risk of Nosocomial Infections: A Prospective Controlled Trial

Start date: June 2007
Phase: N/A
Study type: Interventional

With the construction of a new medical teaching ward with features designed to reduce hospital-acquired infections, we hypothesized that the design of the new ward was the major factor that contributed to the improved outcomes and designed a prospective, controlled study to examine this hypothesis.

NCT ID: NCT00438269 Completed - Critical Illness Clinical Trials

Pilot Study of the Utility of Empiric Antibiotic Therapy for Suspected ICU-Acquired Infection

Start date: February 2003
Phase: Phase 2
Study type: Interventional

Infection developing in the intensive care unit is a common complication of critical illness, but notoriously difficult to diagnose. A definite diagnosis based on the most reliable tests usually is not possible for at least two days. It is unclear what the optimal management approach should be while awaiting the results of diagnostic tests. In some circumstances, broad spectrum antibiotics are started with a plan to adjust them once the results of cultures are available. Observational studies show that this results in greater antibiotic use, and the risk of superinfection and resistance. In other circumstances, antibiotics may be withheld pending the results of cultures, a strategy that leads to a delay in therapy when cultures are positive, and that may be associated with a worse clinical outcome. We undertook a randomized pilot study to address the question: "In a critically ill patient for whom clinicians are uncertain whether infection may be present, and in whom potential sites of infection have been managed by removing or changing invasive devices, can a policy of delaying antibiotic treatment until cultures are available reduce the risks of excessive antibiotic use, without increasing the risks associated with delayed therapy?" Recognizing that the question has not been formally addressed before, and that approaches to clinical management are both widely divergent and passionately held, our pilot study tested the feasibility and acceptability of undertaking a larger trial with sufficient power to determine equivalence.

NCT ID: NCT00273949 Active, not recruiting - Clinical trials for Nosocomial Infection

Lactulose for the Prevention of Nosocomial Infections in Children

Start date: January 2006
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the ability of lactulose, a prebiotic agent, to prevent hospital acquired infection in children