Nonsuicidal Self Injury Clinical Trial
Official title:
Abnormal Neural Pain Empathic Processing in Adolescents With Non-suicidal Self-Injury
Nonsuicidal self-injury (NSSI) is defined as direct, deliberate bodily harm without suicidal intention. In recent years, growing evidence suggests that NSSI has become a worldwide public health issue. People with NSSI behaviors, especially adolescents, commonly exhibit emotion-related and interpersonal problems. Pain empathy represents an essential basal domain of socio-emotional processing and refers to the ability to empathize, connect and share with others' pain. However, altered empathic processing has not been systematically examined in adolescents with NSSI. To this end, the current functional magnetic resonance imaging (fMRI) study will recruit one group of NSSI adolescents (n=40) and one healthy control (HC) group (n=40), to compare their neural activity regarding pain empathy processing, which is measured by blood oxygenation level-dependent (BOLD) fMRI. The investigators included conditions of physical pain empathy (stimuli depicting noxious stimulation to the limbs) and affective pain empathy (stimuli depicting faces expressing pain) as well as corresponding control stimuli. The investigators hypothesize that compared to HC, NSSI adolescents show increased empathic reactivity to physical pain stimuli in salience and arousal related brain regions but decreased empathic reactivity to affective pain empathic stimuli.
n/a
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT05343039 -
Technology Enhanced Adolescent Mental Health (TEAM)
|
N/A | |
Recruiting |
NCT05656001 -
Neuro- and Biofeedback in Nonsuicidal Self-injury
|
N/A | |
Recruiting |
NCT04420442 -
Scar Resection and Reconstruction With Integra and Split Skin Grafts in Patients With Non-Suicidal Self-Inflicted Scars
|
N/A | |
Recruiting |
NCT05981677 -
Social Feedback and Dysfunctional Risk Taking in NSSI Adolescents
|
||
Recruiting |
NCT05907421 -
Emotion Regulation Dysfunctions in NSSI Adolescents in Naturalistic Contexts
|
||
Recruiting |
NCT05981612 -
Impact of Emotional Reactivity on Dysfunctional Decision-Making in NSSI Adolescents
|
||
Completed |
NCT05247190 -
Treating Self-criticism in Adolescents: a Study With Single-case Experimental Design
|
N/A | |
Recruiting |
NCT04498143 -
Single-Session Intervention Targeting Self-Injurious Behavior in Adolescents
|
N/A | |
Recruiting |
NCT06424613 -
Effects of Lithium on Suicide Prevention in Adolescents and Young Adults With Bipolar Disorder in China
|
||
Not yet recruiting |
NCT05325944 -
Digital Mental Health Intervention for Nonsuicidal Self-Injury in Young Adults
|
N/A |