Dynamic Changes of Circulating Tumor DNA in Surgical Lung Cancer Patients

Status Completed

Clinical Trial Summary

Previous study showed circulating tumor DNA levels reflect the total systemic tumor burden. Circulating tumor DNA levels should decrease after complete surgery and could be increase as tumor recurrence. Few study investigated the half time of circulating tumor DNA in lung cancer patients that no criterion has been established of how to use it for surveillance.

Clinical Trial Description

For lung cancer patients who received surgery, multiple time of plasma will be collected before or after surgery. A series of mutations will be detected in plasma before surgery based on next generation sequencing. The positive mutation will be traced after surgery and in follow up. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02965391
Study type	Observational [Patient Registry]
Source	Peking University People's Hospital
Contact
Status	Completed
Phase
Start date	November 2016
Completion date	November 2019

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