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Non-Small Cell Lung Cancer clinical trials

View clinical trials related to Non-Small Cell Lung Cancer.

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NCT ID: NCT02364804 Completed - Clinical trials for Non-small Cell Lung Cancer

A Study to Evaluate the Efficacy of Anti-emetic Drug Upon the Combination Chemotherapy for Non-small Cell Lung Cancer

Start date: April 2012
Phase:
Study type: Observational

The purpose of this study is to evaluate the efficacy of anti-emetic drug Aprepitant upon the combination chemotherapy of nedaplatin and docetaxel for non-small cell lung cancer (NSCLC).

NCT ID: NCT02358473 Completed - Clinical trials for Non-Small Cell Lung Cancer

Study of Mogamulizumab + Docetaxel in Subjects With Non-small Cell Lung Cancer

Start date: January 2015
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety of mogamulizumab in combination with docetaxel in adult subjects with previously treated locally advanced or metastatic non-small cell lung cancer.

NCT ID: NCT02357836 Completed - Clinical trials for Non-small Cell Lung Cancer

Neoadjuvant Itraconazole in Non-small Cell Lung Cancer

Start date: June 2015
Phase: Early Phase 1
Study type: Interventional

The purpose of this study is to determine the pharmacodynamics effects of itraconazole in early-stage non-small cell lung cancer.

NCT ID: NCT02349412 Completed - Depression Clinical Trials

Early Palliative Care With Standard Care or Standard Care Alone in Improving Quality of Life of Patients With Incurable Lung or Non-colorectal Gastrointestinal Cancer and Their Family Caregivers

Start date: April 2015
Phase: Phase 3
Study type: Interventional

The study intervention consists of the early integration of palliative care services into standard oncology care in an outpatient setting for patients with advanced lung and non-colorectal gastrointestinal malignancies who are not being treated with curative intent. The palliative care services provided to patients randomized to the intervention will be provided by board-certified physicians and/or advanced practice nurses and will focus on the following areas: (1) developing and maintaining the therapeutic relationship with the patients and family caregivers; (2) assessing and treating patient symptoms; (3) providing support and reinforcement of coping with advanced cancer in patients and family caregivers; (4) assessing and enhancing prognostic awareness and illness understanding in patients and family caregivers; (5) assisting with treatment decision-making; and (6) end-of-life care planning.

NCT ID: NCT02347917 Completed - Clinical trials for Non-Small Cell Lung Cancer

A Study of BBI608 in Combination With Pemetrexed and Cisplatin in Adult Patients With Malignant Pleural Mesothelioma

Start date: February 2015
Phase: Phase 1/Phase 2
Study type: Interventional

This is an open-label, multicenter, phase 1/2 study of BBI608 in combination with pemetrexed and cisplatin chemotherapy as a 1st line treatment for Malignant Pleural Mesothelioma (MPM).

NCT ID: NCT02340208 Completed - Clinical trials for Non-Small Cell Lung Cancer

A Phase I/II Open-Label, Non-Randomized Dose Escalation Study of Immunoconjugate L-DOS47

Start date: May 2012
Phase: Phase 1/Phase 2
Study type: Interventional

The primary purpose of this research study is to evaluate how safe, how well tolerated and how effective a range of doses of L-DOS47 in patients with non-squamous non-small cell lung cancer when given as a monotherapy.

NCT ID: NCT02338583 Completed - Clinical trials for Non-small Cell Lung Cancer

Powered Surgical Stapler in VATS Lung Resection Procedures in China

Start date: December 1, 2014
Phase: N/A
Study type: Observational

This prospective, single-arm multi-center study will provide clinical data in an observational setting using the Echelon Flex™ 45 and 60 Powered ENDOPATH® Stapler Articulating Endoscopic Linear Cutters (study Endocutter). Individuals undergoing VATS lobectomy for suspected or confirmed Non Small Cell Lung Cancer (NSCLC), or individuals undergoing VATS diagnostic wedge resection in accordance with their institution's Standard of care (SOC), and who meet study entry criteria, may be enrolled. Study procedures will include a wedge resection, wedge resection followed by lobectomy of the same lobe, or lobectomy.

NCT ID: NCT02337530 Completed - Clinical trials for Non-Small Cell Lung Cancer

Selumetinib in Patients Receiving Pemetrexed and Platinum-based Chemotherapy in Advanced or Metastatic KRAS Wildtype or Unknown Non-Squamous NSCLC

Start date: May 26, 2015
Phase: Phase 2
Study type: Interventional

The purpose of this study is to find out what effects a new drug, selumetinib, has on lung cancer when receiving standard chemotherapy with pemetrexed and platinum-based chemotherapy.

NCT ID: NCT02321046 Completed - Clinical trials for Non-Small Cell Lung Cancer

An epidemiOlogy Study to deteRmine the Prevalence of EGFR (Epidermal Growth Factor Receptor) muTations in RUSsian Patients With Advanced NSCLC (Non-Small Cell Lung Cancer).

ORTUS
Start date: September 2, 2015
Phase:
Study type: Observational

This is a multicentre, non-interventional, prospective study to be carried out in representative oncology departments / institutions in order to determine the prevalence of EGFR mutations in treatment-naive Russian patients with cytologically verified advanced NSCLC in Russia.

NCT ID: NCT02319408 Completed - Clinical trials for Non-small Cell Lung Cancer

Immune Boost In Non-Small Cell Lung Cancer

RadImmune
Start date: April 2016
Phase: N/A
Study type: Interventional

Insufficient migration and activation of tumour specific effector T cells seems to be the one important reason for inadequate host anti-tumour immune response. Ionizing radiation can induce a variety of immune responses. The goal of this randomized trial is to assess if a preoperative single fraction low dose radiation is able to improve anti-tumour immune response in operable early stage lung cancer.