Biological Response to Tamoxifen (TAM) in Patients With Breast Cancer Non

Clinical Trial Summary

The biological response to treatment with tamoxifen in the preoperative situation is studying in this protocol. This study will enrolls patients with non-metastatic breast cancer HR +. The relationship between the CYP2D6 polymorphism, pharmacokinetics and biological efficacy of TAM will be studied.

See also
	Status	Clinical Trial	Phase
	Completed	`NCT02901223` - The Impact of Oncoplastic Breast Surgery on the Oncological Safety and Patient Satisfaction	N/A
	Terminated	`NCT01563588` - Support and Rehabilitation Protocol for Non Metastatic Breast Cancer Patients in Complete Remission After Chemotherapy	N/A

See also

Status

Clinical Trial

Phase

Completed

NCT02901223 - The Impact of Oncoplastic Breast Surgery on the Oncological Safety and Patient Satisfaction

N/A

Terminated

NCT01563588 - Support and Rehabilitation Protocol for Non Metastatic Breast Cancer Patients in Complete Remission After Chemotherapy

N/A

Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.

Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.

Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

NCT number	NCT01220076
Study type	Interventional
Source	Institut Cancerologie de l'Ouest
Contact
Status	Completed
Phase	Phase 2
Start date	September 2009
Completion date	October 2016

Biological Response to Tamoxifen (TAM) in Patients With Breast Cancer Non Metastatic RH+ — TAM

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms