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Non-melanoma Skin Cancer clinical trials

View clinical trials related to Non-melanoma Skin Cancer.

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NCT ID: NCT05842421 Completed - Clinical trials for Non-melanoma Skin Cancer

Imaging Methods for the Diagnosis of Non-melanoma Skin Cancer and Its Precursors

Start date: April 21, 2021
Phase: N/A
Study type: Interventional

Prospective, unicentric study that examines if imaging devices like total body photography, dermoscopy, optical coherence tomography and in vivo reflectance confocal microscopy as an addition to clinical examination lead to a benefit for patients in the diagnosis of non-melanoma skin cancer and their precursors

NCT ID: NCT04334824 Completed - Hypertension Clinical Trials

Hydrochlorothiazide and Risk of Skin Cancer

Start date: May 27, 2019
Phase:
Study type: Observational

The purpose of this study is to determine whether the use of hydrochlorothiazide is associated with an increased risk of skin cancer compared with the use of angiotensin-converting enzyme (ACE) inhibitors. More specifically, the investigators will assess the risk of non-melanoma and melanoma skin cancer. The investigators hypothesize that the use of hydrochlorothiazide is associated with an increased risk of skin cancer compared with ACE inhibitors. The investigators will carry out separate population-based cohort studies using administrative health databases from seven Canadian provinces and the United States. The study cohort will be defined by the initiation of hydrochlorothiazide or an ACE inhibitor, with follow-up until an incident diagnosis of non-melanoma or melanoma skin cancer. The results from the separate sites will be combined to provide an overall assessment of the risk of non-melanoma and melanoma skin cancer in users of hydrochlorothiazide.

NCT ID: NCT04123678 Completed - Melanoma Clinical Trials

DERM Health Economics Study

Start date: February 26, 2020
Phase:
Study type: Observational

This study aims to provide an initial assessment of the potential impact DERM could have on the number of onward referrals for a face to face dermatologist review and/or biopsy from a teledermatology-based service, and to improve the understanding of the patient pathways that exist.

NCT ID: NCT04116983 Completed - Clinical trials for Non-melanoma Skin Cancer

DERM NMSC Validation Study

Start date: June 26, 2020
Phase:
Study type: Observational

This study aims to establish the effectiveness of an Artificial Intelligence (AI) algorithm (DERM) to determine the presence of Basal Cell Carcinoma (BCC) and Squamous Cell Carcinoma (SCC) and frequently observed benign conditions, when used to analyse images of skin lesions taken by commonly available smart phone cameras.

NCT ID: NCT03693937 Completed - Clinical trials for Non-melanoma Skin Cancer

A Retrospective Evaluation of Superficial Radiation Therapy (SRT) and Non-Melanoma Skin Cancer (NMSC)

Start date: November 15, 2018
Phase:
Study type: Observational

Non-Melanoma Skin Cancer (NMSC) is the most commonly occurring type of skin cancer, and predominantly comprises (98%) Basal Cell Carcinomas (BCC) and Squamous Cell Carcinomas (SCC). About 3.3 million people in the United States (U.S.) are diagnosed with NMSC annually, equating about 5.4 million BCCs and SCCs. Low-dose Superficial Radiation Therapy (SRT) effectively destroys BCC and SCC without any invasive cutting, bleeding or stitching. There is no need for anesthesia, no risk of infection or scarring and no need for reconstructive plastic surgery. Healing time is quick with minimal to no post-treatment downtime or lifestyle restrictions. It is therefore both a viable and highly desirable alternative to invasive, painful and higher-risk surgical procedures. This study will utilize retrospective chart analysis to evaluate the outcomes of SRT-100™ therapy on NMSC lesions over a long-term post-treatment period.

NCT ID: NCT03607578 Completed - Malignant Melanoma Clinical Trials

Test of Interventions to Prevent Skin Cancer Among Danes on Vacation in High UV Index Sunny Destinations

Start date: August 1, 2018
Phase: N/A
Study type: Interventional

The aim of the study is to test a series of developed effective interventions targeting Danes going on vacation to sunny destinations to decrease sunburn by increasing use of shade, hats, protective clothing, and sunscreen to prevent skin cancer in the Danish population. It has been estimated that up to 90 % of all skin cancers could be avoided by behavioral changes. One of the main sources of UVR exposure in the Danish population is vacations to destinations with high UV index (UVI).

NCT ID: NCT03458117 Completed - Clinical trials for Squamous Cell Carcinoma

T-VEC in Non-melanoma Skin Cancer

20139157 T-VEC
Start date: April 19, 2018
Phase: Phase 1
Study type: Interventional

Evaluation of the mechanism of Action of talimogene laherparepvec (T-VEC) in patients with locally advanced non-melanoma skin cancer.

NCT ID: NCT03253666 Completed - Melanoma Clinical Trials

Nurses' Health Study and Health Professionals Follow-Up Study (Dermatological Component)

Start date: January 2017
Phase:
Study type: Observational [Patient Registry]

To determine the relationships of dietary factors with the subsequent risk of dermatological diseases (such as skin cancers and inflammatory or autoimmune dermatoses) in a cohort of female registered nurses and male health professionals.

NCT ID: NCT03246412 Completed - Melanoma (Skin) Clinical Trials

Nevus Doctor Clinical Decision Support for GPs

Start date: January 17, 2018
Phase: N/A
Study type: Interventional

The study investigates if a computer-based clinical decision support tool for skin cancer may improve the diagnostic accuracy of general practitioners (GPs). The aim of the program is to help GPs increase their diagnostic accuracy, in particular regarding the selection of suspicious skin lesions that need biopsy or referral to specialist health care for further assessment. Half of the physicians in the trial will have the clinical decision support tool available during consultations, while the other half has no such tool available. We hypothesize that general practitioners using the clinical decision support tool will have a higher number of correct classifications of skin lesions compared to doctors without the tool.

NCT ID: NCT03131713 Completed - Clinical trials for Non-melanoma Skin Cancer

Preoperative Acetaminophen and Carbohydrate Loading

Start date: July 1, 2016
Phase: Phase 3
Study type: Interventional

The study's goal is to assess impact of preoperative acetaminophen and oral carbohydrate drinks on pain and functional status experienced by patients undergoing Mohs micrographic surgery for non-melanoma skin cancers. Patients are randomly assigned to receive standard of care or preoperative acetaminophen 1000 mg and Gatorade sports drinks 2 packets before surgery. Patients are then asked to rate their level of pain, anxiety, thirst, hunger, fatigue on a scale of 0-100 on day of surgery before surgery has started, after clearance of skin cancer, and at the end of the visit. Patients are contacted by phone 48 hours after their surgery to assess their maximum level of post-operative pain (rated from 0-100), usage of over the counter or prescribed pain medications, and presence of complications e.g. bleeding, infection, dehiscence. Differences in perioperative functional status and pain medication usage are compared between patients in control and intervention groups.