Clinical Trials Logo
  1. Home
  2. Non-infectious Uveitis
  3. NCT01032915

Safety and Efficacy of AIN457 in Patients With Quiescent Non-infectious Uveitis — ENDURE  

Non-infectious Uveitis Clinical Trial

Official title:
A 24 Week Multi-center, Randomized, Double-masked, Placebo Controlled, Dose-ranging Phase III Study of AIN457 Versus Placebo for Maintaining Uveitis Suppression When Reducing Systemic Immunosuppression in Patients With Quiescent, Non-infectious Intermediate, Posterior or Panuveitis.

Clinical Trial Summary

This study will assess the safety and efficacy of AIN457 as adjunctive therapy for the treatment of intermediate uveitis, posterior uveitis, or panuveitis requiring systemic immunosuppression.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01032915
Study type Interventional
Source Novartis
Contact
Status Terminated
Phase Phase 3
Start date February 2010
Completion date June 2011
View Details
See also
  Status Clinical Trial Phase
Not yet recruiting NCT05928754 - Prospective CoHoRt Of Non-infectious Intermediate, pOsterior or panuveitiS N/A
Terminated NCT00646425 - The Safety and Efficacy of Basiliximab as Maintenance Therapy in Subjects With Stable, Noninfectious Uveitis Phase 2
Terminated NCT00456482 - Safety and Efficacy of Fluocinolone Acetonide Intravitreal Implant Phase 2/Phase 3
Recruiting NCT00720928 - Flucinolone Acetonide Implant for Treating Refractory Ocular Behcet's Disease Phase 4
Completed NCT04018599 - Comparison of PK and Tolerability of MSB11022 Administered by AI or PFS Phase 1
Terminated NCT02951975 - Ozurdex® in Patients With Non-infectious Uveitis Affecting the Posterior Segment of the Eye
Active, not recruiting NCT03634475 - A Safety Study of Intravitreal PP-001 in Patients With Chronic, Non-Infectious Uveitis Phase 1/Phase 2
Completed NCT04207983 - A 48 Week Study to Evaluate the Efficacy and Safety of Two (2) EYS606 Treatment Regimens in Subjects With Active Chronic Non-infectious Uveitis (CNIU) Phase 2
Completed NCT02748512 - Utilization and Safety of the Mk II Inserter and the Safety of the FAI Insert in Non-Infectious Uveitis Phase 3
Recruiting NCT02706704 - Intravitreal Adalimumab Versus Subcutaneous Adalimumab in Non-infectious Uveitis Phase 2
Not yet recruiting NCT04105452 - Study to Evaluate PL8177 in Subjects With Non Infectious Uveitis (NIU) Phase 2
Terminated NCT01090310 - Safety and Efficacy of AIN457 in Patients With Quiescent Non-infectious Uveitis Phase 3
Completed NCT01694186 - Safety and Efficacy of an Injectable Fluocinolone Acetonide Intravitreal Insert Phase 3
Completed NCT03308045 - Evaluation of EYS606 in Patients With Non-infectious Posterior, Intermediate or Panuveitis Phase 1/Phase 2
Completed NCT00468871 - Safety and Efficacy of Fluocinolone Acetonide Intravitreal Implant vs Standardized Therapy Phase 2/Phase 3