Safety and Efficacy Study of DSP-Visulex for the Treatment of Anterior Uveitis

Non-Infectious Anterior Uveitis Clinical Trial

Official title:
A Randomized, Parallel Group, Double-masked, Active-controlled Phase 1/2 Clinical Trial to Evaluate the Efficacy and Safety of Dexamethasone Sodium Phosphate Visulex System for the Treatment of Non-infectious Anterior Uveitis

Status Completed

Clinical Trial Summary

The purpose of this study is to determine the efficacy, safety, and tolerability of dexamethasone sodium phosphate Visulex (DSP-Visulex) after repeated-dose administration in patients with acute anterior uveitis.

Clinical Trial Description

This is a multicenter, randomized, parallel group, double-masked, active- controlled study. Subjects will be enrolled and randomized to either 8 % or 15% DSP-Visulex with placebo drops or Vehicle-Visulex (V-Visulex) with prednisolone acetate 1% eye drops. All subjects will receive concomitant treatment with cyclopentolate. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02309385
Study type	Interventional
Source	Aciont Inc
Contact
Status	Completed
Phase	Phase 1/Phase 2
Start date	October 2014
Completion date	March 3, 2017

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT05042609` - A Study of TRS01 in Subjects With Active Non-infectious Anterior Uveitis Including Subjects With Uveitic Glaucoma	Phase 3
Completed	`NCT02406209` - A Safety and Efficacy Study of NS2 in Patients With Anterior Uveitis	Phase 2
Not yet recruiting	`NCT04426734` - Evaluation of DEXTENZA in the Management of Pain and Inflammation in Patients With Anterior Uveitis Compared to Standard of Care Topical Corticosteroids	Phase 4
Completed	`NCT04222712` - A Study to Evaluate TRS01 Eye Drops in Participants With Active Non-infectious Anterior Uveitis	Phase 1/Phase 2
Completed	`NCT03131154` - SOLACE Trial - A Phase 3 Trial in Subjects With Non-infectious Anterior-uveitis.	Phase 3