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A Study to Investigate the Effects of Ketoconazole on LBH589 in Patients With Advanced Solid Tumors

Neoplasms Clinical Trial

Official title:
A Phase IB, Study to Investigate the Effect of Ketoconazole, a CYP3A4 Inhibitor, on Oral LBH589 and to Assess the Efficacy and Safety of Oral LBH589 in Patients With Advanced Solid Tumors.

Clinical Trial Summary

The primary purpose of this open-label study is to investigate the interaction of ketoconazole, a liver enzyme inhibitor, on oral LBH589 in adult patients with advanced solid tumors. The extension phase of the study will evaluate the safety and efficacy of LBH589 in patients with advanced solid tumors.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00503451
Study type Interventional
Source Novartis
Contact
Status Completed
Phase Phase 1
Start date September 2007
View Details
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