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Effects of Aerobic Exercise on Lean Non-alcoholic Fatty Liver Disease (NAFLD)

Non-alcoholic Fatty Liver Disease Clinical Trial

Official title:
Effects of Aerobic Exercise on Lean Non-alcoholic Fatty Liver Disease

Clinical Trial Summary

NAFLD is increasingly being identified in lean individuals, especially in Chinese population. Among the NAFLD patients, the lean NAFLD accounts for 15.9%-23.0%. Previous studies showed that the lean NAFLD individuals might have a higher risk of severe hepatic disease than those obese individuals. However, the effects of aerobic exercise on the reduction of liver fat content and metabolic risk factors in lean NAFLD individuals remain unknown. In this randomized controlled trial, we will examine the effect of a 3-month exercise training (aerobic exercise) on liver fat content and metabolic risk factors in lean NAFLD individuals.

Clinical Trial Description

The whole study is divided into four phases: recruitment phase, training phase (1 month, aim to gradually adapt patients to the target exercise intensity), implementation phase (3 months), and follow-up phase (9 months). And the subjects are randomly assigned to two groups: aerobic exercise intervention group and control group. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04882644
Study type Interventional
Source The First Affiliated Hospital with Nanjing Medical University
Contact
Status Active, not recruiting
Phase N/A
Start date May 14, 2021
Completion date October 2022
View Details
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