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Validation of HepaFat-Scan for Noninvasive Measurement of Steatosis in Youth

Non-alcoholic Fatty Liver Disease Clinical Trial

Official title:
Validation of HepaFat-Scan for Noninvasive Measurement of Steatosis in Youth

Clinical Trial Summary

The purpose of this study is to see if the HepaFat-Scan (a special sequence of images done in a MRI) can accurately detect the amount of fat in the liver.

Clinical Trial Description

The leading cause of liver disease for both adults and children in the US is nonalcoholic fatty liver disease (NAFLD), an obesity-related liver disease closely associated with the metabolic syndrome. NAFLD increases the risk of liver disease but also increases risk of type II diabetes, cardiovascular disease (CVD) and the metabolic syndrome. Invasive liver biopsy has been considered the best diagnostic tool for confirming NAFLD. This study will establish magnetic resonance imaging (MRI) / magnetic resonance spectroscopy (MRS) as a quantitative noninvasive "virtual biopsy" and benefit the health of children with liver diseases by decreasing risk and improving diagnosis. Specifically, in NAFLD, this fat quantification protocol will be broadly useful in future research studies, including therapies for NAFLD as well as for patient diagnosis and follow-up. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02461212
Study type Interventional
Source Emory University
Contact
Status Completed
Phase N/A
Start date July 1, 2015
Completion date March 17, 2017
View Details
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