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Nocturnal Enuresis clinical trials

View clinical trials related to Nocturnal Enuresis.

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NCT ID: NCT05368246 Completed - Clinical trials for Urinary Incontinence

Safety and Performance of UCon for the Treatment of the Symptoms of Overactive Bladder (OAB) / Bowel Dysfunction (BD)

Start date: February 15, 2022
Phase: N/A
Study type: Interventional

This clinical investigation is a single-arm, prospective, multicentre, early feasibility study, which is used to evaluate the device design of UCon with respect to initial clinical safety and device performance in a small number of subjects. UCon is a medical device for treatment of the symptoms of overactive bladder (OAB) and bowel disorders (BD). It electrically stimulates the dorsal genital nerve (DGN) through the skin to obtain modulated behaviour of the bladder/bowel musculature e.g., suppress undesired bladder/bowel activity to relieve the symptoms of the patient.

NCT ID: NCT05306639 Not yet recruiting - Nocturnal Enuresis Clinical Trials

Treatment of Monosymptomatic Nocturnal Enuresis

Start date: February 1, 2023
Phase: N/A
Study type: Interventional

A prospective randomized trial to study the effect of spinal magnetic stimulation versus posterior tibial neuromodulation in the treatment of monosymptomatic nocturnal enuresis.

NCT ID: NCT05214131 Recruiting - Clinical trials for Urinary Incontinence

Randomized Study Of Novel Enuresis Alarm vs Standard Bedwetting Alarm

Start date: April 29, 2022
Phase: N/A
Study type: Interventional

Identify the dry night rate in patients using the GoGoband® nocturnal enuresis device vs a standard Pflaundler bedwetting alarm.

NCT ID: NCT05190601 Completed - Enuresis Clinical Trials

Uroflowmetry in Children With Enuresis Nocturnal

Start date: January 1, 2020
Phase:
Study type: Observational [Patient Registry]

Background: Enuresis nocturna is an important social and psychological problem in children. Uroflowmetry is an important test used to investigate lower urinary tract symptoms.. Objective:To evaluate the uroflowmetry (UFM) results of children with nocturnal enuresis (NE). Method: The uroflowmetry findings of healthy and visualized children without any urinary symptoms and who were prospectively admitted to the urology and pediatric surgery outpatient clinic with the complaint of Enuresis nocturna between January 2020 and July 2021 were compared. Information (anamnesis, physical examination, radiology results and laboratory tests) and uroflowmetry results of NE and healthy children included in the study were recorded.

NCT ID: NCT05178641 Completed - Nocturnal Enuresis Clinical Trials

Overnight Pant Study for Children With Nocturnal Enuresis

Start date: January 13, 2022
Phase: N/A
Study type: Interventional

This study will evaluate the in-use tolerance of an absorbent disposable underwear pant developed for children with nocturnal enuresis by assessing adverse events. In addition product performance will be assessed by the parent at home via a daily diary.

NCT ID: NCT05151081 Completed - Clinical trials for Overactive Bladder Syndrome

Overactive Bladder Syndrome

Start date: February 3, 2020
Phase:
Study type: Observational

Purpose: A lot of etiological factors related to overactive bladder (OAB) has been investigated. However, the role of primary nocturnal enuresis (NE), which is characterized with childhood night time incontinence, in the etiology of OAB is controversial. This study aims to evaluate the effect of NE in patients diagnosed with OAB. Metod Between january-september 2021, the data of patients who applied to the urology outpatientclinic with OAB symptoms were collected. Patients with a history of chronic systemic disease, previous medical treatment for OAB and who did not accept to join the study were excluded. According to the diagnosis of childhood NE, patients were divided into two groups. Demographic data hav been recorded. Frequency of incontinence, number of day time void and nocturia were evaluated according to a 3 day voiding diary. Inaddition, max. Urinary flowr atio (Qmax), bladder Wall thickness and postvoid residual volüme rates were determined using uroflowmetry and pelvic ultrasound.

NCT ID: NCT05126732 Recruiting - Clinical trials for Circadian Rhythm Disorders

Ganglion Cell Thickness in Enuresis Nocturna

Start date: January 2022
Phase:
Study type: Observational [Patient Registry]

The precise role of the intrinsic circadian regulatory mechanism behind the pathogenesis of enuresis is not fully understood, but in theory, circadian rhythm irregularity may be the primary pathogenic mechanism not only for urinary outflow mechanisms but also for nocturnal bladder function. The proximity between SCN centers that control AVP release, sleep/arousal, voiding, and baroreregulation may provide the basis for circadian rhythm disturbance in one or more of these biological functions. Ganglion cells containing melanopsin pigment in the retina transmit the information they receive from the outside world about the light-dark state to the SCN via the retinohypothalamic pathway. Peripapillary retinal nerve fiber layer (RNFL) thickness, optic nerve head and macula are examined most frequently for the diagnosis of glaucoma and the detection of progression with optical coherence tomography (OCT). If differences in ganglion cell thickness can be detected using OCT in these children, a new avenue in Enuresis Nocturna may be opened.

NCT ID: NCT04676139 Recruiting - Nocturnal Enuresis Clinical Trials

The Safety and Efficacy of Fluoxetine for Refractory Primary Mono-symptomatic Nocturnal Enuresis in Children

Start date: July 1, 2020
Phase: Phase 3
Study type: Interventional

To determine whether there is a role for the selective serotonin reuptake inhibitors, fluoxetine, as therapy in the treatment of refractory primary monosymptomatic nocturnal enuresis in children , and whether there are side effects involved.

NCT ID: NCT04620356 Recruiting - Nocturnal Enuresis Clinical Trials

Effect of Use of DryNites Absorbent Pants on the Rate of Spontaneous Resolution of Paediatric Nocturnal Enuresis (NE)

Start date: February 21, 2020
Phase: N/A
Study type: Interventional

Children vary in the age at which they achieve night-time dryness; in almost all cases children will stop bed-wetting without any need for treatment. Use of absorbent pants for the management of nocturnal enuresis is controversial regarding the impact on the speed at which children become dry throughout the night. The aim of this study is to determine the effect of using DryNites absorbent pants in children with monosymptomatic nocturnal enuresis on the speed they become dry throughout the night compared with removing absorbent pants.

NCT ID: NCT04545931 Recruiting - Clinical trials for Primary Monosymptomatic Nocturnal Enuresis

Posterior Tibial Nerve Stimulation Vs Desmopressin In Children With Primary Monosymptomatic Nocturnal Enuresis

PTNS
Start date: March 15, 2020
Phase: Phase 4
Study type: Interventional

Nocturnal enuresis is a worldwide health problem frequently encountered in childhood . It affects 18 % of younger school- age children in Egypt. It is the most frequent (85%) type of enuresis in children (Eberdt-GoĊ‚abek et al, 2013), . Nocturnal enuresis includes monosymptomatic nocturnal enuresis with no day time urinary symptoms and non monosymptomatic nocturnal enuresis that accompanied by day time urinary symptoms . It can cause severe psychological and social distress to children and their parents . The currently recommended treatment such as alarms , antidiuretic hormone and anticholenergics are not effective in all children with significant relapse rate . Although it's mechanism of action is not fully elucidated , posterior tibial nerve stimulation is safe and acceptable, with evidence of potential clinical effect for both bladder and bowel dysfunction (Bellette et al, 2009). This study will investigate the effect of posterior tibial nerve stimulation on primary monosymptomatic nocturnal enuresis in children.