Clinical Trials Logo

Nocturnal Blood Pressure clinical trials

View clinical trials related to Nocturnal Blood Pressure.

Filter by:
  • None
  • Page 1

NCT ID: NCT06022133 Completed - Clinical trials for Obstructive Sleep Apnea of Adult

Sodium, Nocturnal Blood Pressure and Nocturnal Pauses in Breathing

ROSA
Start date: January 3, 2018
Phase: N/A
Study type: Interventional

A reduction of dietary sodium intake reduces blood pressure and risk of cardiovascular disease.

NCT ID: NCT04971720 Recruiting - Obesity Clinical Trials

PRECISION-BP: Precision Chronopharamacotherapy Targeting NP-RAAS-BP Rhythm Axis

PRECISION-BP
Start date: February 18, 2022
Phase: Phase 2/Phase 3
Study type: Interventional

Obese individuals have a higher prevalence of nocturnal hypertension and non-dipping blood pressure (BP). These conditions are associated with an increased risk of cardiovascular (CV) events and death. Natriuretic Peptides (NPs) are hormones produced by the heart which directly regulate BP by causing dilation of blood vessels and by removing sodium and water from the body. NPs have a 24-hour day-night rhythm and this controls the day-night rhythm of BP as well. The NP-BP rhythm relationship is broken down in obese individuals. Obese individuals also have lower circulating NP levels. Lower circulating levels of NPs and elevated renin hormone (a part of the Renin-Angiotensin-Aldosterone System [RAAS]) at nighttime may contribute to the high nocturnal blood pressure in obese individuals which puts them at a higher risk of developing CV events. This current study seeks to determine the biological implications of chronopharmacology for synchronizing NP-RAAS-based blood pressure therapy with the physiological diurnal rhythms to restore the normal diurnal rhythm of blood pressure in obese individuals.

NCT ID: NCT03834168 Completed - Obesity Clinical Trials

The Diurnal Rhythm in Natriuretic Peptide Levels

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

The purpose of the study to assess the diurnal rhythm in natriuretic peptide levels and its temporal relationship with nocturnal blood pressure in obese and African-American individuals as compared with lean and white individuals.