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Neurovascular Disorder clinical trials

View clinical trials related to Neurovascular Disorder.

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NCT ID: NCT04888221 Recruiting - Clinical trials for Giant Cell Arteritis

Efficacy of Tocilizumab in Association to Steroids in Giant Cell Arteritis With Cerebro-vascular Involvement

TOGIAC
Start date: September 24, 2021
Phase: Phase 3
Study type: Interventional

A French multicenter randomised and placebo-controlled study recruiting patients who present neurovascular involvement related to GCA (> 60 years) with symptomatic (stroke) or asymptomatic forms. The aim of this study is to assess the efficacy of tocilizumab to induce complete remission of GCA with cerebrovascular involvement (clinical and biological) and absence of clinical and MRI ischemic stroke recurrence at 24 weeks.

NCT ID: NCT04865718 Recruiting - Aneurysm, Brain Clinical Trials

Intraoperative Laser Speckle Contrast Imaging of Cerebral Blood Flow

Start date: June 27, 2019
Phase:
Study type: Observational

The purpose of this research study is to evaluate the ability of laser speckle contrast imaging to visualize blood flow in real time during neurosurgery. Real-time blood flow visualization during surgery could help neurosurgeons better understand the consequences of vascular occlusion events during surgery, recognize potential adverse complications, and thus prompt timely intervention to reduce the risk of stroke. The current standard for visualizing cerebral blood flow during surgery is indocyanine green angiography (ICGA), which involves administering a bolus of fluorescent dye intravenously and imaging the wash-in of the dye to determine which vessels are perfused. Unfortunately, ICGA can only be used a few times during a surgery due to the need to inject a fluorescent dye, and provides only an instantaneous view of perfusion rather than a continuous view. Laser speckle contrast imaging does not require any dyes or tissue contact and has the potential to provide complementary information to ICGA. In this study we plant to collect blood flow images with laser speckle contrast imaging and to compare the images with ICGA that is performed as part of routine care during neurovascular surgical procedures such as aneurysm clipping.

NCT ID: NCT04568161 Recruiting - Breast Cancer Clinical Trials

Effect of Anthracyclines and Cyclophosphamide on Cardiovascular Responses

Start date: August 3, 2020
Phase: N/A
Study type: Interventional

The present study aims to investigate the chronic effect of treatment with doxorubicin and cyclophosphamide on neurovascular control and blood pressure in women undergoing adjuvant treatment for breast cancer.