Correlation of PaCO2 to the Inspired and Expired Oxygen Gradient

Neurosurgery Clinical Trial

— O2 Fraction  

Official title:

Correlation of PaCO2 to the Inspired and Expired Oxygen Gradient

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01513213
• Other study ID #: 5119S-11
• Status: Completed
• Phase: N/A
• First received: January 5, 2012
• Last updated: January 20, 2017
• Start date: October 2011
• Est. completion date: December 2016

Study information

• Verified date: January 2017
• Source: Swedish Medical Center
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The purpose of this study is to evaluate whether a correlation exists between the partial pressure of carbon dioxide existing within arterial blood and the gradient between inhaled and exhaled fractions of oxygen.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 65
• Est. completion date: December 2016
• Est. primary completion date: May 2014
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• Age 18 to 65.

• Scheduled for surgical procedure that will last at least 2 hours.

• Arterial cannulation is planned because of either the complexity of the surgery or patient comorbidity.

• At least two arterial blood gas analyses are planned during the surgery.

Exclusion Criteria:

• No arterial cannulation is necessary or planned for the procedure.

Related Conditions & MeSH terms

• Neurosurgery

Locations

Country	Name	City	State
United States	Swedish Medical Center	Seattle	Washington

Sponsors (1)

Lead Sponsor	Collaborator
Swedish Medical Center

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Correlate the level of carbon dioxide within arterial blood to inspired and expired oxygen gradient.	Compare the levels of carbon dioxide found in the patient's blood to the amounts of carbon dioxide and oxygen in the air that the patient inhales and exhales. If a relationship exists between the levels of carbon dioxide in the blood and the levels of carbon dioxide and oxygen inhaled and exhaled by the patient, anesthesiologists will be able to use this relationship to adjust ventilators during anesthesia without having to take blood from an artery.	At least 2 hours