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MSOT as Non-invasive Biomarker for Diagnosis and Monitoring of Neuromuscular Diseases

Neuromuscular Diseases Clinical Trial

Official title:
Multispectral Optoacoustic Imaging (MSOT) as Non-invasive Biomarker for Diagnosis and Monitoring of Neuromuscular Diseases (MSOT-NMD)

Clinical Trial Summary

The goal of this study is to learn if Multispectral Optoacoustic Tomographs (MSOT) works to diagnose and follow the course of neuromuscular diseases (NMDs) in children. MSOT scans will be obtained from muscle region to measure hemo/myoglobin, collagen and lipid content/signal and oxygenation in patients with neuromuscular diseases. No additional research activities -other than MSOT - will be done during this study. Existing clinical, laboratory and imaging data from standard-of-care procedures will be correlated with the MSOT data. The expected total duration of the study is approximately 36 months. Repeated measurements will be done to evaluate disease progression and the value of MSOT in NMD.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06438965
Study type Observational
Source Children's Hospital of Eastern Ontario
Contact Hanns Lochmuller, Dr.
Phone (613) 737-7600
Email hlochmuller@toh.ca
Status Not yet recruiting
Phase
Start date July 2024
Completion date July 2028
View Details
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