'Fitness To Fly' Tests In Children With Type II Respiratory Failure

Status Completed

Clinical Trial Summary

The conventional hypoxic challenge test might not predict 'fitness-to-fly' equally well in all patients. Patients at risk of hypercapnia with supplemental oxygen are not well studied. Th investigators will study children who have either neuromuscular weakness or central hypoventilation and who require nocturnal or intermittent daytime ventilator support. The study also aims to assess feasibility of a randomised controlled trial (RCT) comparing the standard hypoxic standard test to a modified test designed to better suit children with type two respiratory failure.

Clinical Trial Description

This study will assess feasibility of pulse oximetry (SpO2), end tidal carbon dioxide (ETCO2) and transcutaneous carbon dioxide partial pressure (TcCO2) measurement during a modified Hypoxic challenge test (HCT) in 12 children with neuromuscular weakness and 12 with central hypoventilation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03824223
Study type	Interventional
Source	Great Ormond Street Hospital for Children NHS Foundation Trust
Contact
Status	Completed
Phase	N/A
Start date	February 1, 2019
Completion date	August 31, 2021

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