Neuromuscular Blockade Clinical Trial
Official title:
Comparing Deep Neuromuscular Block and Moderate Neuromuscular Block in Patients Undergoing Laparoscopic Gynaecological Surgeries: Impact on Surgical Satisfaction of Operating Conditions and Patient Satisfaction
This study compares surgeon's satisfaction of operating conditions and patient's satisfaction following laparoscopic gynecological surgeries in two groups of patients, half of whom will receive deep neuromuscular blockade and the other half, moderate neuromuscular blockade.
Deep neuromuscular blockade in anesthesia has been shown to improve operating conditions in
retroperitoneal surgeries, while there is minimal evidence regarding this method in
laparoscopic gynecological procedures.The advantage of improving surgical conditions with a
deep neuromuscular blockade in laparoscopic surgery may however lead to a delayed
neuromuscular recovery and hence a delay in turnover of patients.
Rocuronium will be used for muscle relaxation in order to achieve the necessary depth of
neuromuscular blockade. Sugammadex is a modified cyclodextrin that forms complexes with
rocuronium, reducing free plasma concentrations of rocuronium and reversing its neuromuscular
blocking action from any depth.
The use of rocuronium will therefore aid in achieving a deep neuromuscular blockade which the
investigators postulate will improve surgical conditions and the reversal with sugammadex
will ensure a rapid recovery thereafter.
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