Differential Diagnostics of Etiology of Acute Infections

Neuroinfections Clinical Trial

Official title: Differential Diagnostics of Etiology of Acute Infections Based on the Analysis of Expression of Activation Markers on the Surface of Peripheral Blood Monocytes and Neutrophils.

Status Completed

Clinical Trial Summary

Method for diagnostics of the origin of infections (bacterial vs viral) based on the identification of activation markers of blood neutrophils and monocytes will be developed.

Clinical Trial Description

During the study, method for diagnostics of the origin of infections (bacterial vs viral) based on the identification of activation markers of blood neutrophils and monocytes will be developed.This method will allow to make a diagnosis within an hour after blood sampling.

The expression of the following markers of activation will be studied using flow cytometry:

CD11b, CD11c, CD13, CD16, CD32, CD35, CD38, CD62L, CD64, CD66b, CD88, CD284, HLA-ABC and HLA-DR. ;

Related Conditions & MeSH terms

• Communicable Diseases
• Infection
• Intestinal Infectious Diseases
• Neuroinfections

• NCT number: NCT03161951
• Study type: Observational
• Source: The Republican Research and Practical Center for Epidemiology and Microbiology
• Status: Completed
• Start date: January 3, 2017
• Completion date: December 29, 2018