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Functional and Structural Changes in the Central Nervous System Following Spinal Cord Injury

Spinal Cord Injuries Clinical Trial

Official title:
Functional and Structural Changes in the Central Nervous System Following Spinal Cord Injury

Clinical Trial Summary

Building on recent improvements, state-of-the-art functional MRI will be applied as an advanced diagnostic tool for the lumbosacral cord in spinal cord injury (SCI) patients to characterize the remaining neuronal activity of the motor and sensory neurons. Alterations in the activity pattern will reveal the effect upon task-related spinal cord activity of the lower motor neurons and sensory neurons undergoing trauma-induced neurodegeneration, at a spatial specificity that has not been possible so far. Results of this study will be of crucial importance because SCI patients can only profit from regeneration-inducing therapies if spinal neuronal function is preserved below the level of lesion.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05681936
Study type Observational
Source University of Zurich
Contact Gergely David, Dr.
Phone +41 44 510 72 13
Email gergely.david@balgrist.ch
Status Recruiting
Phase
Start date January 1, 2023
Completion date August 31, 2027
View Details
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