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Clinical Trial Summary

Patients entered into the study will receive ASTX727 orally up to 3 to 8 days prior to receiving Lutathera treatment to determine whether pre-treatment with ASTX727 results in re-expression of somatostatin receptor-2 in patients with metastatic neuroendocrine tumours. The study will use [68Ga]-DOTA-TATE PET to image epigenetic modification of the receptor locus.

Clinical Trial Description


Study Design

Related Conditions & MeSH terms

NCT number NCT05178693
Study type Interventional
Source Imperial College London
Contact Rohini Sharma, MD
Phone 02083833170
Email [email protected]
Status Not yet recruiting
Phase Phase 1
Start date January 10, 2022
Completion date December 31, 2025

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