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Neuroendocrine Tumors clinical trials

View clinical trials related to Neuroendocrine Tumors.

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NCT ID: NCT06038461 Not yet recruiting - Clinical trials for Neuroendocrine Tumors

An Open, Single-center Clinical Study of Surufatinib Combined With Temozolomide and S-1 in the First-line Treatment of Advanced Neuroendocrine Tumors

Start date: September 15, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

This is a prospective, open, single-center study evaluating the efficacy and safety of surufatinib Combined With Temozolomide and S-1 as the first-line treatment of advanced neuroendocrine tumors

NCT ID: NCT06024343 Not yet recruiting - Clinical trials for Pancreatic Neuroendocrine Tumor

Minimally Invasive Pancreatic Enucleation With Main Pancreatic Duct Repair or Reconstruction

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the impact of concomitant main pancreatic duct repair or reconstruction during minimally invasive pancreatic tumor enucleation on long-term patient prognosis and quality of life.

NCT ID: NCT05987176 Not yet recruiting - Clinical trials for Neuroendocrine Tumors

Comparing Adjuvant Treatment With 177Lu-DOTATATE to Best Supportive Care in Patients After Resection of Neuroendocrine Liver Metastases

NELMAS
Start date: November 1, 2023
Phase: Phase 2
Study type: Interventional

An international multi-centre, stratified, open, randomized, comparator-controlled, parallel-group phase II study comparing adjuvant treatment with 177Lu-DOTATATE to best supportive care in patients after resection of neuroendocrine liver metastases.

NCT ID: NCT05973968 Not yet recruiting - Clinical trials for Neuroendocrine Tumor Grade 3

Surufatinib in G3 Neuroendocrine Tumors

Start date: August 2023
Phase:
Study type: Observational

The goal of this observational study is to learn about surufatinib in Refractory Metastatic G3 Neuroendocrine Tumors. The main questions it aims to answer are: - To evaluate the efficacy and safety of surufatinib in the treatment of second-line and posterior-line in G3 neuroendocrine tumors. - To explore the predictive value of blood perfusion parameters in curative effect. Participants will be given surufatinib 300mg QD, po, every 4 weeks as a course of treatment, continuous administration until PD, death or intolerable toxicity.

NCT ID: NCT05967481 Not yet recruiting - Clinical trials for Neuroendocrine Tumors

Evaluation of Study Experiences of Neuroendocrine Tumor Patients

Start date: August 2024
Phase:
Study type: Observational

Taking part in clinical trials usually favors a particular demographic group. But there is limited research available to explain what trial attributes affect the completion of these specific demographic groups. This research will admit a wide range of data on the clinical study experience of neuroendocrine tumor patients to determine which factors prevail in limiting a patient's ability to join or finish a trial. It will also try to analyze data from the perspective of different demographic groups to check for recurring trends which might yield insights for the sake of future patients with neuroendocrine tumor.

NCT ID: NCT05894486 Not yet recruiting - Clinical trials for Neuroendocrine Tumors

Phase II Study to Evaluate the Efficacy and Safety of 177Lu-Dotatate in the First-line Treatment of Patients With Locally Advanced or Metastatic, Somatostatin Receptor-positive G2 or G3 Gastroenteropancreatic Neuroendocrine Tumors

Start date: June 5, 2023
Phase: Phase 2
Study type: Interventional

his was a single-center, single-arm phase II study evaluate the efficacy and safety of Lutetium[177Lu] Oxodotreotide Injection in the first-line treatment of unresectable or metastatic, progressive, G2 or G3, somatostatin receptor positive gastroenteropancreatic neuroendocrine tumours.

NCT ID: NCT05647954 Not yet recruiting - Clinical trials for Melanoma Neuroendocrine Tumors Neuroectodermal Tumors Neoplasms Germ Cell and Embryonal Neoplasms by Histologic Type Neoplasms Neoplasms

A Study of HX008 Plus Transcatheter Arterial Chemoembolization (TACE) in the First-Line Treatment of Subjects With Stage IV (M1c) Melanoma That is Metastatic to the Liver

Start date: December 31, 2022
Phase: Phase 3
Study type: Interventional

The main purpose of this study is to compare the clinical benefit, as measured by Progression-Free Survival (PFS) and Overall Survival(OS), achieved by HX008 Plus Transcatheter Arterial Chemoembolization (TACE) or Temozolomide Plus Transcatheter Arterial Chemoembolization (TACE) in the First-Line Treatment of Subjects With Stage IV (M1c) Melanoma That is Metastatic to the Liver.

NCT ID: NCT05557708 Not yet recruiting - Clinical trials for Carcinoma, Small-Cell Lung

A Safety Study of 212Pb-Pentixather Radioligand Therapy

Start date: July 1, 2024
Phase: Early Phase 1
Study type: Interventional

This is a first-in-human clinical trial evaluating the safety of an alpha-radiation treatment (Lead-212 labelled Pentixather) in patients who have been diagnosed with, and previously treated, for atypical carcinoid lesions of the lung.

NCT ID: NCT05429216 Not yet recruiting - Clinical trials for Rectal Neuroendocrine Tumor

Endoscopic Resection for Small Rectal Neuroendocrine Tumors

Start date: June 2022
Phase: N/A
Study type: Interventional

In previous single center study, both modified cap-assisted endoscopic mucosal resection (mEMR-C) and endoscopic submucosal dissection (ESD) were reported to be effective for the treatment of small rectal neuroendocrine tumors (NETs) and mEMR-C was inferior to ESD for the treatment of small rectal NETs (≤10 mm), as it has shorter operation times and lower hospitalization costs. However, a multicenter randomized controlled trial is needed to prove the universality and generality of these findings.

NCT ID: NCT05316480 Not yet recruiting - Clinical trials for Pancreatic Neuroendocrine Neoplasm

Nimotuzumab in EGFR Highly Expressed Pancreatic Neuroendocrine Neoplasms

Start date: May 1, 2022
Phase: Phase 2
Study type: Interventional

The phase II study is performed to assess the efficacy and safety of Nimotuzumab in patients with stage IV pancreatic neuroendocrine neoplasms and EGFR overexpression.