Childhood Obesity Clinical Trial
Official title:
Maternal Grandmothers in the Born in Guangzhou Cohort Study
The MGBIG is a study exploring cross-generational effects in 5000 women and their children and grandchildren located in Guangzhou, China. Its initial aim is to facilitate research on understanding the interplay between genes and environmental factors on disease etiology and on explaining the cause of the disease from the perspective of "grandmother-mother-child" heredity. Data are collected regarding environmental exposures, lifestyle, and social support on grandmother from birth to old age. Biological samples including blood and tissue samples are collected.
It was previously believed that heredity strictly follows Mendel's laws, but recent studies have found that through placental material exchange, mammals may transfer maternal immune-related factors vertically, thus promoting the protection of "non-heredited maternal antigenic traits". Thus, the transmission of reproductive information across generations is realized. Since the unusual genetic pattern of the X chromosome, grandmother's influence may be gender specific. Since grandchildren were usually took care by grandparents in China, it could be achievable to attach and recruit maternal grandmother together with mother and children. Cohort including three generations of women is rare in Asia at present. In the MGBIG, extensive information including demographic characteristics, lifestyle, history of diseases, mental health, and behaviors is collected from the participants. Longitudinal follow up and surveillance of common chronic diseases are also to be conducted. The MGBIG intends to recruit maternal grandmothers to study the effects of maternal genetic and environmental exposure on the health of their children and grandchildren. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT05437406 -
Family, Responsibility, Education, Support, and Health for Latino Caregivers (FRESH-LC)
|
N/A | |
Completed |
NCT03297541 -
Healthy Kids I-PAL
|
N/A | |
Completed |
NCT05527938 -
Web-based Interventions on Nonalcoholic Fatty Liver Disease (NAFLD) in Obese Children
|
N/A | |
Completed |
NCT05501392 -
South Texas Early Prevention Studies PreK
|
N/A | |
Completed |
NCT03334266 -
Preventing Early Childhood Obesity, Part 2: Family Spirit Nurture, Prenatal - 18 Months
|
N/A | |
Active, not recruiting |
NCT03342092 -
Early Adiposity Rebound Amongst 4-y.o. Children and Overweight Risk Amongst 11-y.o Children : Third Phase of a Cohort Study in Franche-Comté
|
N/A | |
Completed |
NCT06239662 -
Therapeutic Education Groups for Childhood Obesity
|
N/A | |
Withdrawn |
NCT02767830 -
Cleveland Kids Run
|
N/A | |
Not yet recruiting |
NCT02889406 -
Motivation Approach for Childhood Obesity Treatment
|
N/A | |
Completed |
NCT03245164 -
The Effects of Group Exercise and Basketball on Obese Children
|
N/A | |
Completed |
NCT02559076 -
The Eat Right Emirates Healthy Lifestyle Study
|
N/A | |
Completed |
NCT02484976 -
Brain Activation and Satiety in Children: Functional Magnetic Resonance Imaging
|
N/A | |
Completed |
NCT02087774 -
Brief Physical Activity Program to Increase Physical Fitness in Elementary School Children
|
N/A | |
Completed |
NCT01977105 -
Healthy Growth Abbreviated Pilot Study
|
N/A | |
Completed |
NCT01821313 -
CASH- Children Active to Stay Healthy
|
N/A | |
Completed |
NCT01849315 -
Effects of Physical Activity on Disease Risk Factors
|
N/A | |
Completed |
NCT01789671 -
Peer Counseling in Family-Based Treatment for Childhood Obesity
|
N/A | |
Completed |
NCT02637752 -
Nutrition and Physical Activity Counselling
|
N/A | |
Completed |
NCT02799433 -
Evaluation of the Healthy Apple Program in San Francisco
|
N/A | |
Completed |
NCT01246349 -
Motivational Interviewing for Weight Loss
|
N/A |