Neuralgia Clinical Trial
Official title:
DOLORisk: Understanding Risk Factors and Determinants for Neuropathic Pain - Peripheral Physiological Measures as Determinants of Pain Risk
This study evaluates peripheral nervous system function using Multiple Excitability Measures (MEM) to obtain "electrophysiological pain phenotypes"
Using MEM for peripheral sensory and motor axons we want to identify a set of excitability
measures that:
1. Correlate with parameters of clinical pain and of pain processing in existing pain
patients (cross sectional study), with the aim to obtain an objective Pain Biomarker.
2. Predict development of neuropathic pain in susceptible patients (longitudinal study).
Neuropathic Pain Predictor for patients:
i. Undergoing surgical procedures associated with a relatively high risk of developing
neuropathic pain such as thoracotomy and hernia repair ii. Planning to start chemotherapy
with potentially neurotoxic agents such as vincristine
;
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