Neuralgia Clinical Trial
Official title:
Evaluation of the Efficacy, Tolerability, and Safety of 7 Days of Treatment With GRT6010 or Pregabalin in Comparison to Placebo in Subjects With Peripheral Neuropathic Pain.
The purpose of this trial is to determine whether a novel analgesic is effective in treating of neuropathic pain caused by herpetic infection, surgery, or trauma.
This trial evaluates the effectiveness of a novel analgesic in peripheral neuropathic pain in
a mixed patient population. Participants were treated for one week and randomly assigned to
the novel analgesic, pregabalin, or placebo. Pain will be characterized before and at the end
of this period. This trial required the participants to stay at the investigational site for
14 consecutive days.
The enrollment visit took place Day -28 to Day -16. Participants tapered down their existing
medication from Visit 2 (Day -17 to Day -5) to Visit 3 and were given rescue medication
(paracetamol/acetaminophen). At Visit 3 participants were hospitalized (Day -4). The baseline
evaluation period took place from Day -3 to Day -1. Randomization to one of the three
treatment arms was possible after the last assessment on Day - 1 alternatively randomization
took place on Day 1. This was followed by the double-blind treatment period (Day 1 to Day 7).
The participants were follow-up thereafter up to day 36 (Day 34 to 38). Participants were
permitted to resume their previous medication.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Active, not recruiting |
NCT04066933 -
Forms of Cervical Brachial Syndrome Treated With Plasma Concentrate Enriched for A2M
|
||
| Completed |
NCT01202227 -
An Open-Label Long-Term Study Of Pregabalin For The Treatment Of Central Neuropathic Pain
|
Phase 3 | |
| Terminated |
NCT00964990 -
A Study to Evaluate the Efficacy, Safety, and Tolerability of JNJ-42160443 in Patients With Neuropathic Pain (Postherpetic Neuralgia and Post-traumatic Neuralgia)
|
Phase 2 | |
| Completed |
NCT00922987 -
Clinical Study With Lyrica In Patients Suffering From Epilepsy
|
||
| Recruiting |
NCT00740571 -
Amitriptyline or Pregabalin to Treat Neuropathic Pain in Incurable Cancer
|
Phase 3 | |
| Terminated |
NCT02747758 -
Transcranial Direct Current Stimulation (tDCS) in Chronic Neuropathy
|
N/A | |
| Completed |
NCT05464199 -
Home-based EEG Neurofeedback for Chronic Neuropathic Pain
|
Phase 1 | |
| Completed |
NCT02490436 -
Novel Treatment Option for Neuropathic Pain
|
Phase 2 | |
| Completed |
NCT01974791 -
GET Living: Graded Exposure Treatment for Children and Adolescents With Chronic Pain
|
N/A | |
| Completed |
NCT01279018 -
Persistent Pain After Breast Cancer Treatment With Docetaxel
|
N/A | |
| Not yet recruiting |
NCT00944502 -
To Evaluate the Efficacy and Tolerability of the Use of Vitatonus Dexa Compared to Dexamethasone in Patients With Neuralgia of Various Origins
|
Phase 3 | |
| Completed |
NCT02957851 -
EMONO for the Treatment of Peripheral Neuropathic Pain
|
Phase 2 | |
| Completed |
NCT02180880 -
Symptom Based Treatment of Neuropathic Pain
|
Phase 4 | |
| Active, not recruiting |
NCT01508676 -
Effects of Pennsaid on Clinical Neuropathic Pain
|
N/A | |
| Completed |
NCT00631943 -
A Study to Evaluate the Efficacy and Safety of Pregabalin (Lyrica) for the Treatment of Nerve Pain
|
Phase 3 | |
| Completed |
NCT03973983 -
Comparison of Ultrasound-guided Transgluteal and Finger-guided Transvaginal Pudendal Nerve Block Techniques
|
N/A | |
| Terminated |
NCT03296111 -
Patients With Ocular Neuropathic Pain: Description of Pain and Impact on Their Quality of Life
|
||
| Not yet recruiting |
NCT06398847 -
Virtual Reality (VR) Self-Hypnosis Software
|
N/A | |
| Terminated |
NCT02460107 -
Botulinum Toxin Type A for Neuropathic Pain in Patients With Diabetic Peripheral Polyneuropathy
|
Early Phase 1 | |
| Recruiting |
NCT01788410 -
MRI-Guided Cryoablation to Alleviate Pain in Head, Neck and Spine
|