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Neuralgia, Postherpetic clinical trials

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NCT ID: NCT03094195 Terminated - Clinical trials for Post-herpetic Neuralgia

Dose Response Study of EMA401 in Patients With Post-herpetic Neuralgia (PHN)

EMPHENE
Start date: June 27, 2017
Phase: Phase 2
Study type: Interventional

This study was designed to characterize dose response, and evaluate safety and efficacy of three different doses of EMA401 compared to placebo in patients with post-herpetic neuralgia (PHN).

NCT ID: NCT02412917 Terminated - Herpes Zoster Clinical Trials

A Comparative Study of FV-100 vs. Valacyclovir for the Prevention of Post-Herpetic Neuralgia

Start date: June 2015
Phase: Phase 3
Study type: Interventional

This is a multicenter, randomized, double-blind, parallel-group, active controlled comparative study of the safety and efficacy of 2 dosing regimens of FV-100 versus valacyclovir administered for 7 days in subjects with uncomplicated AHZ(acute herpes zoster).

NCT ID: NCT01886313 Terminated - Clinical trials for Postherpetic Neuralgia

Civamide Nasal Solution for Postherpetic Neuralgia of the Trigeminal Nerve

Start date: March 2014
Phase: Phase 2
Study type: Interventional

Herpes zoster (commonly referred to as "shingles") results from the reactivation of the varicella-zoster virus acquired during a primary infection, usually chickenpox. The virus lays dormant in the cells of the nerves until activated. Once activated, patients develop a characteristic red blistering rash which crusts and heals in 2 - 4 weeks. Postherpetic neuralgia (PHN), the term for pain persisting after the herpes zoster (HZ) eruption heals, is the most common and most feared complication of herpes zoster infection. The drug, Civamide is thought to desensitize the nerves and decrease the pain of PHN. This is the pharmacologic rationale for its use in the nose in postherpetic neuralgia of the trigeminal nerve, a nerve that is in the nose and transmits pain from the face. The objective of this study is to evaluate the safety and efficacy of intranasally administered Civamide (0.01%) for the treatment of moderate to severe daily pain associated with postherpetic neuralgia of the trigeminal nerve. Neuropathic pain must have persisted for ≥ 12 months.

NCT ID: NCT01744522 Terminated - Clinical trials for Postherpetic Neuralgia

Leech Therapy for Postherpetic Neuralgia

ZoHir
Start date: September 2012
Phase: N/A
Study type: Observational

The purpose of this study is to investigate, whether leech therapy for the treatment of postherpetic pain improves pain and sensory function. Therefore 20 patients with PHN undergoing leech therapy at the investigators outpatient clinic will be included in this observational trial.

NCT ID: NCT01678924 Terminated - Clinical trials for Neuralgia, Postherpetic

A Safety and Efficacy Study of AGN-214868 in Patients With Postherpetic Neuralgia

Start date: January 2013
Phase: Phase 2
Study type: Interventional

This is a safety and efficacy study of AGN-214868 in patients with postherpetic neuralgia (PHN).

NCT ID: NCT01603394 Terminated - Clinical trials for Postherpetic Neuralgia

Pilot Study Of Pregabalin And Prediction Of Treatment Response In Patients With Postherpetic Neuralgia

Start date: October 2012
Phase: Phase 4
Study type: Interventional

The primary objective is to explore whether sensory symptom cluster analysis is useful for predicting treatment response in Postherpetic Neuralgia.

NCT ID: NCT01124097 Terminated - Clinical trials for Post Herpetic Neuralgia

Eslicarbazepine Acetate as Therapy in Post-Herpetic Neuralgia

Start date: September 2010
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to assess the efficacy of Eslicarbazepine acetate (ESL) as therapy in subjects with Post-herpetic Neuralgia (PHN) over a 15 week treatment phase.

NCT ID: NCT01088256 Terminated - Clinical trials for Postherpetic Neuralgia

Efficacy of Etoricoxib on Peripheral Hyperalgesia

Start date: February 2011
Phase: Phase 2
Study type: Interventional

The purpose of the study is to determine the efficacy of etoricoxib on pain patients. The investigators assume that patients with neuropathic pain will have greater pain relief then patients on placebo.

NCT ID: NCT01058642 Terminated - Clinical trials for Postherpetic Neuralgia

Study to Assess the Efficacy, Safety, and Tolerability of ADL5747 in Participants With Postherpetic Neuralgia

Start date: January 2010
Phase: Phase 2
Study type: Interventional

The primary purpose of this study is to evaluate the analgesic efficacy of ADL5747 in participants with postherpetic neuralgia (PHN). The secondary objective of this study is to evaluate the safety, tolerability, and pharmacokinetics of ADL5747.

NCT ID: NCT00976534 Terminated - Pain Clinical Trials

Study to Evaluate Efficacy, Safety, Tolerability and Pharmacokinetics of AZD1386 in Patients With Peripheral Neuropathic Pain

AVANT
Start date: September 2009
Phase: Phase 2
Study type: Interventional

The primary aim of this study is to investigate if AZD1386 is efficacious as an analgesic in patients with peripheral neuropathic pain. This will be done by comparing the effect of AZD1386 to placebo ("inactive substance") on pain.