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Nephrolithiasis clinical trials

View clinical trials related to Nephrolithiasis.

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NCT ID: NCT05697250 Recruiting - Renal Stone Clinical Trials

High Versus Low Power Settings During Ureteroscopic Laser Lithotripsy

Start date: January 23, 2023
Phase: N/A
Study type: Interventional

The primary aim of the study is to compare the operative times following ureteroscopic lithotripsy for renal stones with Thulium Fiber Laser using low and high power settings. Secondary aims are to compare the results of low and high power settings in terms of stone free rates, laser time, laser activation patterns, intraoperative and postoperative complications. Patients ≥ 18 years with renal stones (8-25 mm) scheduled for ureteroscopic lithotripsy at the Day Surgery Clinic at Haukeland University Hospital in Bergen, Norway, are eligible for inclusion in the study. After written consent and inclusion, patients are randomised to laser lithotripsy using either low power settings (Group 1: 4-6 Watt, short pulse mode) or high power settings (Group 2: 16-18 Watt, short pulse mode). The ureteroscopic procedures are performed in general anaesthesia using a standardised technique. All patients are followed up with a low dose CT scan 3 months post endoscopically to assess stone free status as well as a consultation at the outpatient clinic. Results and data for the two randomisation groups are compared according to the aims of the study.

NCT ID: NCT05648877 Recruiting - Clinical trials for Retrograde Intrarenal Surgery In Management Of Renal Stones

to Study the Role of Retrograde Intrarenal Surgery in Management of Renal Stones

Start date: October 1, 2020
Phase: N/A
Study type: Interventional

Role Of Retrograde Intrarenal Surgery In Management Of Renal Stones: Single Center Experience

NCT ID: NCT05634434 Recruiting - Renal Stone Clinical Trials

Uric Acid Based Renal Stones: Clinical, Metabolic and Genetic Characterization

Start date: October 1, 2021
Phase:
Study type: Observational

- Reporting prevalence of uric acid based renal stones among patients with nephrolithiasis admitted to Mansoura Urology and Nephrology center (MUNC). - Furthermore, identification of monogenic and polygenic uric acid stone formers. - Identification of factors associated uric acid stone recurrence as well as determinants of laterality in patients with uric acid based renal stones

NCT ID: NCT05598671 Recruiting - Kidney Calculi Clinical Trials

Percutaneous Nephrolithotomy Without a Ureteral Catheter

Start date: November 3, 2022
Phase: N/A
Study type: Interventional

Conventional Percutaneous nephrolithotomy (PCNL) surgery requires the patient to first undergo retrograde transurethral ureteroscopic insertion of the ureteral catheter in the lithotomy position, and then change the patient to the prone position. However, repeated operation on the ureter can bring about immediate and long-term negative effects, such as ureteral false way formation, ureteral damage, perforation, avulsion, catheter insertion into the vena cava, pricking the kidney, increased postoperative pain, urinary extravasation, scar formation, and ureteral narrowing. The study planned to perform the operation in the prone position without reverse insertion of a ureteral catheter in the PCNL surgery.

NCT ID: NCT05598645 Recruiting - Kidney Stone Clinical Trials

Thulium Fiber Laser (TFL) Versus Holmium MOSES Laser for Ureteroscopic Management of Kidney Stones

Start date: August 16, 2022
Phase: N/A
Study type: Interventional

This study aims to compare the efficacy and safety of both types of lasers, Holmium MOSES and TFL, in management of kidney stones requiring treatment.

NCT ID: NCT05578807 Recruiting - Kidney Calculi Clinical Trials

Total Tubeless Percutaneous Nephrolithotomy Without a Ureteral Catheter

Start date: September 28, 2022
Phase: N/A
Study type: Interventional

Total tubeless Percutaneous nephrolithotomy (PCNL) is a modified surgical method of PCNL surgery, that is, there is no indwelling nephrostomy tube and double-J tube during PCNL surgery. Compared with traditional PCNL surgery, it has the advantages of reducing pain, shortening operation time and reducing operation cost. Since this procedure was first performed in 2004, several randomized clinical studies have verified the safety and efficacy of total tubeless PCNL. Conventional total tubeless PCNL surgery requires the patient to first undergo retrograde transurethral ureteroscopic insertion of the ureteral catheter in the lithotomy position, and then change the patient to the prone position. However, a large number of literature reports and the surgical experience of PCNL in the past 20 years tell the investigators that the reverse insertion of ureteral catheter can cause many recent surgical complications.The study planned to perform the operation in the prone position without reverse insertion of a ureteral catheter in the total tubular PCNL surgery.

NCT ID: NCT05535816 Recruiting - Clinical trials for Ultrasound Therapy; Complications

Accuracy of Ultrasound for Detecting Residual Fragments During RIRS

Start date: March 27, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the accuracy of ultrasound and traditional fluoroscopy to find the residual fragments before retrograde intrarenal surgery is complete. This would ultimately limit the need for radiation exposure and improve the quality of clinical care given to patients and healthcare teams.

NCT ID: NCT05460559 Recruiting - Stone, Kidney Clinical Trials

Endoscopic Combined Intrarenal Surgery Versus Multi-Tract Percutaneous Nephrolithotomy for Complex Renal Stones:

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to compare outcomes of endoscopic combined intrarenal surgery (ECIRS) with the multi-tract percutaneous nephrolithotomy for management of complex renal stones.

NCT ID: NCT05460247 Recruiting - Clinical trials for Kidney Stone Prevention

Protein Sources Urinary Stone Risk

Start date: October 30, 2022
Phase: N/A
Study type: Interventional

Prior studies have shown that the source of dietary protein can have a significant impact on urinary stone risk. However, whey and plant protein isolates have not been compared. This is an important distinction as protein supplements fortified foods are increasingly popular. Herein, we seek to investigate the effect of different protein supplements, in an otherwise identical diet, on urinary stone risk.

NCT ID: NCT05417568 Recruiting - Kidney Stones Clinical Trials

Oxalate-Driven Host Responses in Kidney Stone Disease

Start date: May 19, 2023
Phase: N/A
Study type: Interventional

This study is looking to understand the role of oxalate on kidney stone development and immunity. This study will enroll healthy participants and participants with calcium oxalate kidney stones (CaOx KS). Participants will be in this study for about 3 weeks, consume controlled diets, and provide blood and urine specimens.