Nephrogenic Diabetes Insipidus During Prolonged Sevoflurane Sedation in

Clinical Trial Summary

The investigators aim to retrospectively explore the electronic medical records of all patients who were admitted to the Intensive Care Unit (ICU) of the UZ Brussels in the last 10 years (March 1st 2011- March 1st 2021) and who received prolonged sedation (>24h) with sevoflurane.

See also
Status	Clinical Trial	Phase
Recruiting	`NCT05190744` - PB to Treat Hereditary Nephrogenic Diabetes Insipidus, ADPKD Treated With Tolvaptan, and Severely Polyuric Patients With Previous Lithium Administration	Phase 2
Recruiting	`NCT06065852` - National Registry of Rare Kidney Diseases
Not yet recruiting	`NCT05307042` - Decline in Renal Concentration Ability in Lithium Treated Patients
Completed	`NCT00478335` - Pharmacologic Treatment of Congenital Nephrogenic Diabetes Insipidus	N/A

See also

Status

Clinical Trial

Phase

Recruiting

NCT05190744 - PB to Treat Hereditary Nephrogenic Diabetes Insipidus, ADPKD Treated With Tolvaptan, and Severely Polyuric Patients With Previous Lithium Administration

Phase 2

Recruiting

NCT06065852 - National Registry of Rare Kidney Diseases

Not yet recruiting

NCT05307042 - Decline in Renal Concentration Ability in Lithium Treated Patients

Completed

NCT00478335 - Pharmacologic Treatment of Congenital Nephrogenic Diabetes Insipidus

N/A

Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.

Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.

Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

NCT number	NCT04939753
Study type	Observational
Source	Universitair Ziekenhuis Brussel
Contact
Status	Completed
Phase
Start date	May 26, 2021
Completion date	April 1, 2023

Nephrogenic Diabetes Insipidus During Prolonged Sevoflurane Sedation in the ICU: a Retrospective Analysis

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms