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Volume of Perirenal Fat and Chronic Kidney Disease

Nephrectomy Clinical Trial

Clinical Trial Summary

The perirenal fat may alter renal function by secreting fibrotic inflammatory agents when accumulates during obesity. Nephrectomy for renal tumor is a model that would provide tissue samples to test this hypothesis. Renal tumor could itself be responsible for inflammation and fibrosis in its environment. This study aims to measure the influence of the tumor on his kidney Environment and fat and define molecular markers not influenced by renal tumor. The main objective is to compare the inflammation of the perirenal fat taken in two locations in the same patient, in contact and 4 cm from the outer edge of the tumor, each patient as his own control. The secondary objective is to compare the degree of interstitial fibrosis of the renal cortex in the same sampling methods.

Clinical Trial Description

n/a

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02870621
Study type Observational
Source Centre Hospitalier Universitaire de Nice
Contact Guillaume FAVRE, Dr
Phone 4 92 03 88 24
Email favre.g@chu-nice.fr
Status Recruiting
Phase N/A
Start date July 2012
View Details
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