Age Gene/Environment Susceptibility Reykjavik Study

Neoplasms Clinical Trial

— AGES  

Official title:

Association of Pre-diagnostic Vitamin D Levels and Survival in Older Individuals With Cancer

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03269656
• Other study ID #: IHA
• Secondary ID: NO1-AG-1-2100ZIA
• Status: Completed
• Phase: N/A
• First received: August 30, 2017
• Last updated: August 30, 2017
• Start date: January 1, 2002
• Est. completion date: December 31, 2014

Study information

• Verified date: August 2017
• Source: Icelandic Heart Association
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

5764 men and women in Iceland, aged 66 to 96 years entered the Ages Gene/Environment Susceptibility (AGES) - Reykjavik Study. Serum 25(OH)D was measured in 5,519 of all 5,764 (96%) participants at study entry in year 2002 through 2006. The main emphasis was on exploring whether pre-diagnostic serum levels of 25(OH)D were associated with survival after cancer diagnosis.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 5764
• Est. completion date: December 31, 2014
• Est. primary completion date: January 31, 2006
• Accepts healthy volunteers: No
• Gender: All
• Age group: 66 Years to 98 Years

Eligibility

Inclusion Criteria:

• To participate in the AGES-Reykjavik study

Exclusion Criteria:

• To be diagnosed with cancer before study entry

Related Conditions & MeSH terms

• Neoplasms

Locations

Country	Name	City	State
n/a

Sponsors (2)

Lead Sponsor	Collaborator
Icelandic Heart Association	University of Iceland

References & Publications (1)

Harris TB, Launer LJ, Eiriksdottir G, Kjartansson O, Jonsson PV, Sigurdsson G, Thorgeirsson G, Aspelund T, Garcia ME, Cotch MF, Hoffman HJ, Gudnason V. Age, Gene/Environment Susceptibility-Reykjavik Study: multidisciplinary applied phenomics. Am J Epidemiol. 2007 May 1;165(9):1076-87. Epub 2007 Mar 10. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Overall survival	The association between pre-diagnostic 25(OH)D levels in cancer patients and overall survival	From date of diagnosis until death or censored at end of the follow-up (December 31, 2014)
Primary	Cancer survival	The association between pre-diagnostic 25(OH)D levels in cancer patients and cancer survival	From date of diagnosis until cancer death or censored at the end of the follow-up (December 31, 2014)
Secondary	Cancer diagnosis	The association between pre-diagnostic 25(OH)D levels and cancer risk	From date of blood draw (study entry) until cancer diagnosis, death or end of the observation period (December 31, 2014) whichever occurred first

External Links

•   Age, Gene/Environment Susceptibility-Reykjavik Study: Multidisciplinary Applied Phenomics