Vitamin D Levels and Survival in Cancer Patients

Neoplasms Clinical Trial

Official title:

Association of Pre-diagnostic Vitamin D Levels and Survival in Older Individuals With Cancer

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03266887
• Other study ID #: HI14010102
• Status: Completed
• Phase: N/A
• First received: August 28, 2017
• Last updated: August 28, 2017
• Start date: January 1, 2002
• Est. completion date: December 30, 2006

Study information

• Verified date: August 2017
• Source: Icelandic Heart Association
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Using the population-based data sources in Iceland and the well-characterized AGES-Reykjavik cohort, our overarching aims are on exploring whether pre-diagnostic serum levels of 25-hydroxyvitamin D (25(OH)D) among older individuals living in Iceland were associated with survival after cancer diagnosis. We also wanted to assess the risk of being diagnosed with cancer in association with 25(OH)D levels. In this population living just south of the arctic circle, vitamin D levels largely depend on dietary- and supplemental sources.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 5764
• Est. completion date: December 30, 2006
• Est. primary completion date: December 30, 2006
• Accepts healthy volunteers: No
• Gender: All
• Age group: 66 Years to 98 Years

Eligibility

Inclusion Criteria:

To be part of the AGES-Reykjavik Study, initiated between 2002 and 2006.

Exclusion Criteria:

Diagnosed with cancer at study entry

Related Conditions & MeSH terms

• Neoplasms

Locations

Country	Name	City	State
n/a

Sponsors (2)

Lead Sponsor	Collaborator
Icelandic Heart Association	University of Iceland

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Pre-diagnostic 25(OH)D levels and cancer risk	We tested the association between pre-diagnostic 25(OH)D levels and risk of being diagnosed with cancer	Participants without cancer were followed from the study entry since 2002 until cancer diagnosis, death or end of the observation period whichever occurred first (December 31, 2014)
Primary	Overall mortality among cancer patients	We tested the association between pre-diagnostic 25(OH)D levels and total survival	Patients were followed from date of diagnosis since 2002 until death or censored at end of the follow-up (December 31, 2014)
Secondary	Cancer-specific mortality among cancer patients	We tested the association between pre-diagnostic 25(OH)D levels and cancer survival	Patients were followed from date of diagnosis since 2002 until death or censored at end of the follow-up (December 31, 2014)

External Links

•   Age, Gene/Environment Susceptibility-Reykjavik Study: Multidisciplinary Applied Phenomics