Neoplasms Clinical Trial
Official title:
Comparison of the Healing of Chemotherapy-Induced Oral Mucositis Using Oral Defense Toothpaste Versus Crest Toothpaste and Magic Mouth Rinse
The purpose of this study is to determine whether Oral Defense Toothpaste causes accelerated healing of chemotherapy-induced oral mucositis.
A pilot study showed that patients with chemotherapy-induced oral mucositis experienced
accelerated healing of their oral mucositis by brushing with Oral Defense Toothpaste.
In this study, participants experiencing up to grade 2 chemotherapy-induced oral mucositis
will be split into two arms. The first arm (test arm) will receive Oral Defense Toothpaste
and be required to brush three times per day, for 8 days. The second arm (control arm) will
receive Crest Toothpaste and be required to brush three times per day, for 8 days. Patients
in the control arm will be provided Magic Mouth Rinse, if needed. Healing of oral mucositis
lesions will be evaluated at days 1 and 8. Quality of life assessment (determination of
pain/loss of oral function) will be determined using a daily questionnaire.
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