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GW572016 With Docetaxel and Trastuzumab for the Treatment Of Untreated ErbB2 Over-Expressing Metastatic Breast Cancer

Neoplasms, Breast Clinical Trial

Official title:
An Open-label, Multicenter, Phase I/II Dose Escalation Study of Oral GW572016 in Combination With Docetaxel (Taxotere) Plus Trastuzumab (Herceptin) in Subjects Previously Untreated for ErbB2-overexpressing Metastatic Breast Cancer

Clinical Trial Summary

This study was designed to be two-part study (Phase I/Phase II). Part I was designed to find the optimal (best) doses of GW572016, docetaxel, and trastuzumab when given together. Part II was designed to evaluate the tumor response rate (shrinkage or lack of growth) in patients receiving all three drugs compared to patients receiving only docetaxel and trastuzumab.

Clinical Trial Description

Phase II part was cancelled before it started. Participants were only enrolled in the phase I part and NOT the phase II part. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00251433
Study type Interventional
Source Novartis
Contact
Status Terminated
Phase Phase 1
Start date September 26, 2005
Completion date June 22, 2022
View Details
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