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A Study of Intravenous XMT-1107 in Patients With Advanced Solid Tumors — XMT-1107  

Neoplasm Metastasis Clinical Trial

Official title:
A Phase 1 Study of the Safety and Pharmacokinetics of XMT-1107 Administered as an Intravenous Infusion Once Every Three Weeks to Patients With Advanced Solid Tumors

Clinical Trial Summary

XMT-1107 has been shown in nonclinical studies to slow the growth of tumors. These effects may result from blocking the growth of new blood vessels that help the tumors survive.

Clinical Trial Description

This is an open-label, ascending-dose study of XMT-1107 administered intravenously over 90 minutes every 21 days (1 cycle). Blood sampling for PK analyses will be performed immediately prior to dosing and after dosing. Adverse events will be graded according to the National Cancer Institute (NCI) Common Terminology Criteria (CTC) version 4.0 (CTCAE v4.0) ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01011972
Study type Interventional
Source Mersana Therapeutics
Contact
Status Completed
Phase Phase 1
Start date March 2010
Completion date September 2013
View Details
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