Clinical Trials Logo
  1. Home
  2. Neonatal Respiratory Distress
  3. NCT06372951
  4. Details
NCT06372951 Clinical Trial

Lung Ultrasound in Neonatal Intensive Care Units

Neonatal Respiratory Distress Clinical Trial

Official title:
Role of Lung Ultrasound in Assessment of Neonatal Respiratory Distress

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT06372951
Other study ID # Lung ultrasound in neonate
Secondary ID
Status Not yet recruiting
Phase
First received
Last updated
Start date May 1, 2024
Est. completion date March 2026

Study information
Verified date April 2024
Source Assiut University
Contact Esraa Talat Fawzy, Master
Phone 01061846361
Email esraatalat883@gmail.com
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Identification of lung diseases causing neonatal respiratory distress by lung ultrasound as a tool that can replace x-ray .

Description:

- Lung disease is the most common cause of neonatal respiratory distress. - It can result in respiratory failure and death in severe cases. - The mortality rate is approximately 11%:32%. - Identification of the etiology of lung disease is important for neonatologists. - Traditionally, chest X-ray has been considered as the most valuable imaging modality for the diagnosis of lung diseases, but it unavoidably causes radiation damage to the patient. - Neonates are susceptible to radiation because they have rapidly dividing cells that cannot repair mutated DNA. - The risk of cancer induction in infants receiving a single small dose of radiation is 2-3 times higher than the average population and 6-9 times higher than the risk from an exposure of a 60-year-old patient. - New imaging modalities have been introduced in clinical practice in recent years such as lung ultrasound. - One of the most common causes of neonatal respiratory distress that can be diagnosed by ultrasound is :Respiratory Distress Syndrome: - Respiratory distress syndrome.. is a major cause of neonatal mortality. - It mainly occur in preterm infants due to structural and functional lung immaturity. - Pulmonary surfactant insufficiency is an important pathogenesis in respiratory distress syndrome. - The ultrasonic features of respiratory distress syndrome are: Compact B-Lines, white lung appearance, abnormality in pleural line (thick and irregular),lung consolidation. - Lung ultrasound has the advantages of : - Non-ionizing. - Easy to operate. - Low coast. - Portable for bedside use. - The imaging is performed in real-time. - Thus making it as a potential tool to be used in neonatal intensive care units.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 132
Est. completion date March 2026
Est. primary completion date March 2026
Accepts healthy volunteers No
Gender All
Age group 1 Day to 28 Days
Eligibility Inclusion Criteria: - Neonates in neonatal intensive care units Exclusion Criteria: - Patients with poor-quality of lung ultrasound image. - Subcutaneous emphysema.

Study Design

Related Conditions & MeSH terms

Intervention

Device:
• Ultrasound
A device that use ultrasonic waves as a way to image the internal organs and tissues of the body in order to diagnose the different diseases.

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Assiut University

Outcome
Type Measure Description Time frame Safety issue
Primary Identifying causes of neonatal respiratory distress - To evaluate lung ultrasound accuracy and reliability in diagnosing pulmonary disease in neonates in comparison to x rays Baseline
See also
  Status Clinical Trial Phase
Terminated NCT05030012 - Maintaining Optimal HVNI Delivery Using Automatic Titration of Oxygen in Preterm Infants N/A
Active, not recruiting NCT04780412 - Efficacy of Misoprostol in Prevention of Neonatal Respiratory Morbidity in Parturient at Early Term Elective Caesarian Section Phase 3
Completed NCT05257499 - In-person Versus Online Debriefing in HBB N/A
Terminated NCT04096235 - A Study to Evaluate the Use of the Neotech RAM Nasal Cannula for CPAP and Bi-PAP Application in Infants 28-42 Weeks Gestation in a Neonatal Intensive Care Unit (NICU) N/A
Recruiting NCT05737095 - Study of the Feasibility of Early Lung Ultrasound in Neonatal Respiratory Distress in Premature Newborns Born Between 32 Weeks of Amenorrhea and 36 Weeks Plus 6 Days of Amenorrhea, Hospitalized in the Neonatal Pediatrics and Intensive Care Units of the Dijon University Hospital
Completed NCT06171867 - PNEUMACRIT Device for Neonatal Cardio Respiratory Monitoring N/A
Recruiting NCT02030691 - Tolerance of nHFPV Versus nCPAP in Neonatal Respiratory Distress N/A
Not yet recruiting NCT06292338 - Lung Sonar in Neonatal Respiratory Disorders
Not yet recruiting NCT05144724 - Volume Targeted Mask Ventilation Versus Pressure Ventilation in Preterm Infants N/A
Completed NCT06198478 - Tandem: Skin-to-skin Transfer From the Delivery Room to the Neonatal Unit
Recruiting NCT06356909 - Study of PREMEdication Before Laryngoscopy in Neonates in France
Recruiting NCT03239327 - Vaginal Misoprostol to Improve the Neonatal Respiratory Outcome N/A
Completed NCT04051762 - A Comparative Study Between Postextubation of Preterm Infants Into High-Flow Nasal Cannulae V.S Nasal Continuous Positive Airway Pressure
Not yet recruiting NCT03899597 - The Role of ARTificial Uterine CONtractions in Perinatal Respiratory Morbidity of Term Infants Delivered by Elective Caesarean Section N/A
Recruiting NCT02978976 - Effect of Antenatal Steroid on Pulmonary Artery Blood Flow Phase 4
Completed NCT06285669 - Effects of Kinesiotaping on Respiratory Muscles in Very Preterm Infants N/A
Recruiting NCT06207994 - PRICO: OPTI Target Range N/A
Recruiting NCT05274386 - Evaluation of the Impact of SpO2 Averaging Time on Performance of an Automatic FiO2 Control System: a Randomized Study N/A
Recruiting NCT02020993 - Urine NT-ProBNP in Neonatal Respiratory Distress N/A
Recruiting NCT04947215 - The Association Between LPCAT1 Genetic Polymorphism and Stress Biomarkers in Neonatal Respiratory Distress Syndrome