Neonatal Respiratory Distress Clinical Trial
Official title:
The Prognostic Value of Urine NT-ProBNP in Neonatal Respiratory Distress
There is a need for a biochemical marker in addition to clinical condition which will help
the physician to understand the clinical progress of the disease.
Urine Nt-proBNP, which does not need any blood sampling and can be collected easily, has not
been evaluated for respiratory distress in newborn.
The investigators aim to evaluate the prognostic value of urine NT-proBNP in respiratory
diseases in newborns by a controlled trial.
Neonatal diseases such as respiratory distress and transient tachypnea of newborn may
require high level of intensive care. On the other hand, some minor difficulties in
respiration can resolve within hours. Therefore, there is a need for a biochemical marker in
addition to clinical condition which will help the physician to understand the clinical
progress of the disease.
Serum NT-ProBNP level has been evaluated in transient tachypnea of newborn and found
compatible with the clinical progress. Urine NT-proBNP has recently been evaluated in patent
ductus arterioses and found compatible with the cardiac progress. However, urine Nt-proBNP,
which does not need any blood sampling and can be collected easily, has not been evaluated
for respiratory distress in newborn.
The investigators aim to evaluate the prognostic value of urine NT-proBNP in respiratory
diseases in newborns by a controlled trial.
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Observational Model: Case Control, Time Perspective: Prospective
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