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Neonatal Infections clinical trials

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NCT ID: NCT02279381 Completed - Neonatal Infections Clinical Trials

Neonatal Package Study in Rural District of Pakistan

Start date: November 2014
Phase: Phase 4
Study type: Interventional

Neonatal mortality has been a notable health issue in Pakistan. Considering the importance of the issue and well recognized interventions the investigators are proposing a randomized controlled trial in a rural district of Pakistan which will evaluate the effectiveness of a neonatal package comprised of the standard neonatal care, Kangaroo Mother Care (KMC) and application of chlorhexidine compared with standard neonatal care coupled with application of chlorhexidine and essential neonatal care alone. The investigators anticipate that this study will provide an evidence base way forward benefiting the children of Pakistan.

NCT ID: NCT00920530 Completed - Clinical trials for Streptococcus Agalactiae

Real-Time PCR for the Detection of Vaginal Group B Streptococcus Carriage: a Medico-Economic Study

BBFAST
Start date: November 2008
Phase: N/A
Study type: Observational

Group B streptococcus infections may be serious for the neonates. The infection can occur during the birth, by contact with the genital area. That is why the detection of this bacteria is systematically realised in pregnant women between 34 and 37 weeks of amenorrhea in order to give prophylactic antibiotic treatment in case or positive carriage. This strategy presents 2 disadvantages : (1) detection of the group B streptococcus at 34 and 37 weeks of amenorrhea in not predictive of a carriage at delivery, (2) many pregnant women escape from systematic screening, leading to a systematic antibiotic treatment, which means useless costs, and useless antibiotic exposure with resistant bacteria selection. Real time polymerase chain reaction (PCR) allows a rapid detection anytime with no specific microbiological qualification. The aim of the study is to assess the economic outcomes of this strategy and the epidemiological values for St Etienne hospital.

NCT ID: NCT00743691 Completed - Neonatal Infections Clinical Trials

Impact Study of Community Based Treatment of Neonatal Infection by Health Extension Workers on Neonatal Mortality

Start date: June 2009
Phase: N/A
Study type: Interventional

The purpose of the study is to determine whether community based management of infections with antibiotics administered by health extension workers reduce all cause mortality in neonates after the first day of life compared to current MOH IMNCI model of referral to hospital

NCT ID: NCT00713726 Completed - Pain Clinical Trials

Tramadol Versus Fentanyl for Post-Operative Analgesia in Newborn Infants

Start date: January 2006
Phase: Phase 3
Study type: Interventional

In newborn infants submitted to surgical procedures, tramadol may provide an effective analgesia and decrease the time on mechanical ventilation support and the time to achieve full enteral feeding.