Association of Plasma Transfusions and Invasive Fungal Infection

Neonatal Infection Clinical Trial

— PT  

Official title:

Association of Plasma Transfusions and Invasive Fungal Infection

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03149562
• Other study ID #: plasma transfusions
• Status: Recruiting
• Start date: January 1, 2011
• Est. completion date: December 31, 2023

Study information

• Verified date: October 2022
• Source: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
• Contact: Ma Juan, MD
• Phone: 13508300283
• Email: petshi530[@]vip.163.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Although lacking strong evidences, plasma transfusions are commonly used in critically ill neonates. To date, the relationships between plasma transfusions and nosocomial infection remain controversial and no study has reported the relationships between plasma transfusion and invasive fungal infection (IFI)

Description:

Our aim is to explore the association between plasma transfusions and IFI in critically ill neonates

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 500
• Est. completion date: December 31, 2023
• Est. primary completion date: December 31, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 0 Hours to 24 Hours

Eligibility

Inclusion Criteria:

• all critically ill neonates admitted in hospital

Exclusion Criteria:

• severe congenital abnormality;

• died within 24 hours or left neonatal intensive care unit within 24 hours according to their parents' decisions;

• parents' decision not to participate.

Related Conditions & MeSH terms

• Communicable Diseases
• Infections
• Invasive Fungal Infection
• Invasive Fungal Infections
• Mycoses
• Neonatal Infection
• Plasma Administration

Intervention

Drug:
• plasma transfusions
These critical ill neonates with plasma transfusions
• non-plasma transfusions
These critical ill neonates without plasma transfusions

Locations

Country	Name	City	State
China	Department of Pediatrics, Daping Hospital, Third Military Medical University	Chongqing	Chongqing

Sponsors (1)

Lead Sponsor	Collaborator
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	the rate of invasive fungal infection	the rate of invasive fungal infection in plasma transfusions group	100 days