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Mycoses clinical trials

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NCT ID: NCT06285370 Recruiting - Clinical trials for Cutaneous T-Cell Lymphoma

A Study to Evaluate the Efficacy and Safety of KW-0761 in Chinese Subjects With Mycosis Fungoides or Sézary Syndrome Previously Treated With Systemic Therapy

Start date: May 29, 2023
Phase: Phase 4
Study type: Interventional

The purpose of the study is to evaluate the efficacy and safety of mogamulizumab (KW-0761) in chinese subjects with mycosis fungoides or sézary syndrome previously treated with systemic therapy

NCT ID: NCT06285188 Not yet recruiting - Clinical trials for Invasive Fungal Disease

Immunomonitoring of Mold Invasive Infections

IMMUNOFIL
Start date: March 2024
Phase:
Study type: Observational

Mold invasive infections are associated with an important mortality despite optimization of the antifungal treatment. In a few case reports, immune checkpoints inhibitors, initially developed for neoplastic diseases, have shown a potential beneficial effect in such devastating infections by restoring an efficient immune response. The investigators propose a longitudinal monitoring of the adaptative immune response, notably immune checkpoint expression on T cells, during mold invasive infections to help identify the patients who could benefit from the adjunction of immunotherapy and the optimal timing of such strategy.

NCT ID: NCT06235281 Recruiting - Mycosis Fungoides Clinical Trials

Phototherapy and Mogamulizumab in Early Stage MF (PLIGHT)

PLIGHT
Start date: February 2024
Phase: Early Phase 1
Study type: Interventional

This is an open label, single arm, single-center, pilot study of concurrent phototherapy and POTELIGEO (mogamulizumab-kpkc) in early-stage mycosis fungoides.

NCT ID: NCT06220370 Not yet recruiting - Clinical trials for Infection, Bacterial

PATH Study: People With Injecting Related Infections: Assessing Treatment Outcomes for Those Who Are Hospitalised.

PATH
Start date: March 1, 2024
Phase:
Study type: Observational

We seek to characterise the burden and outcomes of and understand the current experience of people who inject drugs admitted to hospital with invasive injecting-related infections, in order to implement and evaluate strategies to improve completion of therapy and reduce patient-directed discharges, with ultimate benefit to the patient and health service.

NCT ID: NCT06207812 Recruiting - Mycosis Fungoides Clinical Trials

Long-term Outcomes Associated With Juvenile-onset Mycosis Fungoides and Lymphomatoid Papulosis

Start date: January 19, 2024
Phase:
Study type: Observational

To follow up with all our participants with juvenile-onset mycosis fungoides, check on their status, and ask them or their parents about long term outcomes associated with their condition.

NCT ID: NCT06190002 Not yet recruiting - Clinical trials for Acute-on-chronic Hepatitis B Liver Failure

Characteristics and Risk Factors for Invasive Fungal Infection With Acute-on-chronic Hepatitis B Liver Failure

Start date: January 20, 2024
Phase:
Study type: Observational

This is a single-center retrospective study. The clinical data of patients with Acute-on-chronic Hepatitis B liver failure who were hospitalized in the Department of Hepatology, Qilu Hospital of Shandong University from January 2010 to July 2023 were collected.

NCT ID: NCT06149247 Recruiting - Clinical trials for Cutaneous T-Cell Lymphoma/Mycosis Fungoides

HyBryte (Synthetic Hypericin) Versus Valchlor (Mechlorethamine) in the Treatment of CTCL

Start date: December 5, 2023
Phase: Phase 2
Study type: Interventional

The objective of this clinical study is to compare the safety and effectiveness of Valchlor versus HyBryte following 12 weeks of treatment.

NCT ID: NCT06137690 Recruiting - Clinical trials for Invasive Fungal Infection

Factors on Therapeutic Drug Monitoring and Safety of Voriconazole in Critically Ill Elderly Patients

Start date: July 1, 2018
Phase:
Study type: Observational

This was a prospective clinical study that all voriconazole-treated adult Chinese patients with invasive pulmonary infection admitted to Zhengzhou Central Hospital affiliated to Zhengzhou University from July 2018 to June 2023. The initial voriconazole serum trough concentration, Correlation of various factors, and risk prediction factors for voriconazole serum trough concentration and hepatotoxicity were compared between elderly and non-elderly patients.

NCT ID: NCT06113081 Not yet recruiting - Clinical trials for Cutaneous T Cell Lymphoma

Real World Experience With Mogamulizumab in the Treatment of Cutaneous T-cell Lymphoma

FIL_MOGA
Start date: January 2024
Phase:
Study type: Observational

This study is designed to describe the clinical activity and safety profile of mogamulizumab at standard dose in the treatment of CTCL patients in real world setting

NCT ID: NCT06105411 Recruiting - Clinical trials for Invasive Fungal Infections

Siderophore-labelled Positron Emission Tomography for Correlating Invasive Fungal InfeCtions

SPECIFIC
Start date: December 1, 2023
Phase:
Study type: Observational

This trial will demonstrate localised uptake of a radiolabelled fungal component (siderophore) in areas of known specific invasive fungal (Aspergillus) infection.