Acute Kidney Injury in Neonates at NICU in Assiut University Children Hospital Descriptive Study

Neonatal Acute Kidney Injury Clinical Trial

Official title:

Acute Kidney Injury in Neonates at NICU in Assiut University Children Hospital Descriptive Study

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT03528837
• Other study ID #: AKI neonates
• Status: Not yet recruiting
• Start date: June 30, 2018
• Est. completion date: August 1, 2019

Study information

• Verified date: May 2018
• Source: Assiut University
• Contact: Mustafa Sh Khalf, Professor
• Phone: +20112110096
• Email: mostafa.tawfeek1[@]med.au.edu.eg
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Acute kidney injury (AKI) is a complex disorder with clinical manifestations ranging from mild dysfunction to complete anuric kidney failure. Its leads to sudden and rapid decline in renal excretory function within hours to days,accompanied by accumulation of nitrogenous waste products such creatinine,urea and other clinically un measured products

Description:

Acute kidney injury (AKI) is an under-recognized morbidity of neonates; the incidence remains unclear due to the absence of a unified definition of AKI in this population and because previous studies have varied greatly in screening for AKI with serum creatinine and urine output assessments. Premature infants may be born with less than half of the nephrons compared with term neonates, predisposing them to chronic kidney disease (CKD) early on in life and as they age. AKI can also lead to CKD, and premature infants with AKI may be at very high risk for long-term kidney problems. AKI in neonates is often multifactorial and may result from prenatal, perinatal, or postnatal insults as well as any combination thereof.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 30
• Est. completion date: August 1, 2019
• Est. primary completion date: July 1, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A to 28 Days

Eligibility

Inclusion Criteria:

• All cases of acute kidney injury in neonates who will be admitted to NICU Assiut University Children Hospital during the duration of the study.

Exclusion Criteria:

• Cases with chronic renal affection Any case with congenital anomalies

Related Conditions & MeSH terms

• Acute Kidney Injury
• Neonatal Acute Kidney Injury
• Wounds and Injuries

Locations

Country	Name	City	State
Egypt	Assiut university children hospital	Assiut

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Diagnosed as acute kidney injury	Diagnosis of acute kidney injury	10-21 days