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NCT05522270 Clinical Trial

Concentrated Growth Factor Versus Platelet Rich Fibrin in Revitalization of Necrotic Young Permanent Incisors

Necrotic Pulp Clinical Trial

Official title:
Concentrated Growth Factor Versus Platelet Rich Fibrin in Revitalization of Necrotic Young Permanent Incisors

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT05522270
Other study ID # 320
Secondary ID
Status Not yet recruiting
Phase N/A
First received
Last updated
Start date September 1, 2022
Est. completion date July 1, 2023

Study information
Verified date August 2022
Source Minia University
Contact ghada tony, doctora
Phone 01117902713
Email ghadatony2003@gmail.com
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Regenerative endodontic procedures (REPs) are the most recent proposal to manage immature permanent teeth with necrotic pulps. So in this study, the investigator will evaluate the clinical and radiographical revitalization success in necrotic young permanent anterior teeth of participants by using Concentrated Growth Factor versus Platelet-Rich Fibrin

Description:

has been entered

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 60
Est. completion date July 1, 2023
Est. primary completion date May 1, 2023
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 6 Years to 11 Years
Eligibility Inclusion Criteria: - Healthy patients with immature permanent incisors - Presence of clinical signs and symptoms of necrosis or chronic apical periodontitis. The chronic apical periodontitis signs and symptoms include little discomfort with intermittent episodes of pus discharge through the sinus tract. Exclusion Criteria 1. Abnormal tooth mobility. - Positive history of allergic reaction, systemic diseases, severe emotional or behavioral problems. - Unrestorable teeth - Abnormal tooth mobility - Children with systemic, severe behavioral, or emotional problems

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• revitalization by concentrated growth factor
modified platelet concentrate

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Ahmad Elheeny

Outcome
Type Measure Description Time frame Safety issue
Primary Clinical success rate Regaining tooth vitality with electric pulp testing Clinical examination includes pain absence, normal tooth mobility, and no sensitivity to percussion one year
Primary Radiographic success using Periapical index (PAI) Criteria of PAI scores:
score "1" normal periapical structure score "2" small changes in bone structures score "3" changes in bone structure with some mineral loss score "4" periodontitis with well-defined radiolucent area score "5" severe periodontitis with exacerbating features		 one year
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