Clinical Trials Logo
  1. Home
  2. Necrotic Pulp
  3. NCT04646538
  4. Details
NCT04646538 Clinical Trial

Volume Assessment of the Periapical Healing Following Regenerative Endodontic Procedures Using Cone- Bean Computed Tomography

Necrotic Pulp Clinical Trial

Official title:
3 D Volume Assessment of the Periapical Healing Following Regenerative Endodontic Procedures Using Cone- Bean Computed Tomography

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04646538
Other study ID # 19832009
Secondary ID
Status Completed
Phase Early Phase 1
First received
Last updated
Start date June 5, 2017
Est. completion date December 30, 2018

Study information
Verified date November 2020
Source Alexandria University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

3D volume assessment was done to evaluate the periapical healing following REPs in mature teeth.

Description:

REPs were done for 10 mature maxillary necrotic teeth with periapical lesions confirmed by digital periapical radiographs. Instrumentation was done using Protaper Next till size X3 (size 30). Pre-operative radiographs also included CBCT scans to measure the 3D volume and area of the periapical lesion to be used as baseline data. The postoperative radiographic examination included: a) digital periapical radiographs taken at 3,6,9, and 12 months to monitor the lesion through out the follow-up period. b)CBCT scan to measure quantitatively the volume and area of the periapical lesion after 12 months follow up

Recruitment information / eligibility
Status Completed
Enrollment 10
Est. completion date December 30, 2018
Est. primary completion date August 20, 2018
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 20 Years to 40 Years
Eligibility Inclusion Criteria: - Necrotic Mature Maxillary anterior teeth with periapical lesions. Exclusion Criteria: - Patients with mobile and fractured teeth

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• Regenerative Endodontics Procedures (REPs)
REPs was done for 10 mature maxillary necrotic teeth with periapical lesions. Instrumentation was done using Protaper Next system till size X3. Irrigation with 1.5 % NaOCl was done in the first visit. in the second visit, bleeding was induced in the canal by irritating the periapical area followed by the application of Biodentine as cervical plug then completion of the coronal restoration.

Locations
Country Name City State
Egypt Alexandria University Alexandria

Sponsors (1)
Lead Sponsor Collaborator
Alexandria University

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary Measurement the volume of periapical lesion preoperatively and comparing it with the new volume after REPs using cone-beam computed tomography. Measuring the volume in mm3 12 months
See also
  Status Clinical Trial Phase
Not yet recruiting NCT04035330 - Effect of Etidronate in Sodium Hypochlorite Versus Sodium Hypochlorite on the Intensity of Postoperative Pain N/A
Completed NCT06418386 - Bacterial Reduction of Rotary Versus Manual Filing System Using Different Irrigants in Primary Molars N/A
Not yet recruiting NCT05522270 - Concentrated Growth Factor Versus Platelet Rich Fibrin in Revitalization of Necrotic Young Permanent Incisors N/A
Completed NCT04606719 - Healing Potentiality Of Blood Clot S-PRF and A-PRF in the Treatment Of Necrotic Mature Single-Rooted Teeth With Chronic Peri-Apical Periodontitis N/A
Not yet recruiting NCT05988788 - Effect of Epigallocatechin-3-Gallate Solution as a Root Canal Irrigant on Post-Operative Pain Intensity and Bacterial Load Reduction in Necrotic Tooth N/A
Completed NCT04983524 - Propolis Versus Calcium Hydroxide on Post-Operative Pain in Patients With Necrotic Pulp N/A
Not yet recruiting NCT06116214 - Effect of Vachellia Nilotica Versus Sodium Hypochlorite as Root Canal Irrigant on Postoperative Pain and Bacterial Load Reduction in Mandibular Premolar Teeth With Necrotic Pulp Phase 4
Not yet recruiting NCT03698188 - Comparative Evaluation of the Regenerative Capacity of Two Platelet Concentrates N/A
Not yet recruiting NCT05289843 - Rosmarinus Officinalis Versus 2.5%Sodium Hypochlorite as Root Canal Irrigants N/A
Not yet recruiting NCT06310044 - Effect of Commiphora Myrrh Solution as a Root Canal Irrigant on Post Operative Pain and Bacterial Load Reduction in Necrotic Tooth N/A
Completed NCT03084601 - Evaluation of Postoperative Pain After Using 3MIX-TATIN Versus Calcium Hydroxide Iodoform Paste In Necrotic Primary Molars Treated by Lesion Sterilization and Tissue Repair Therapy Phase 4
Not yet recruiting NCT03059290 - Incidence of Post-Operative Pain After Single Visit Root Canal Treatment in Necrotic Teeth Using Two Different Rotary Systems (Protaper Nex t& Neolix File) N/A
Completed NCT03708081 - Comparative Evaluation of Different File Systems in Postoperative Pain
Not yet recruiting NCT05419752 - Clinical Assessment of 3 Differant Obturation Sealers on Postoprative Pain and Swelling Phase 2/Phase 3
Completed NCT05775081 - Treated Dentine Matrix and Platelet Rich Fibrin in Induction of Root Formation of Non-Vital Immature Permanent Teeth N/A
Not yet recruiting NCT03009006 - Post Operative Pain and Level of Endotoxins With Calcium Hydroxide and Calcium Hydroxide Mixed With Chlorhexidine in Treating Necrotic Teeth N/A
Not yet recruiting NCT05620147 - Effect of Apical Enlargement to Different Preparation Sizes and Tapers on Pain and Bacterial Reduction in Necrotic Pulp N/A
Not yet recruiting NCT05146713 - Effect of Propolis Nanoparticles on Postoperative Pain and Bacterial Reduction in Mandibular Premolars Phase 2/Phase 3
Not yet recruiting NCT04728386 - Postoperative Pain and Antibacterial Efficacy After Root Canal Irrigation With Curcumin or Sodium Hypochlorite N/A
Not yet recruiting NCT04035070 - Effect of Irrigation With Antibiotic-containing Solutions on Postoperative Pain and Intra-canal Bacteria Phase 4